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Embryonal tumour of possible germline origin v0.7 KRAS Achchuthan Shanmugasundram commented on gene: KRAS: KRAS has been added to the panel for the clinical indication 'R456 Embryonal tumour of possible germline origin' with a green rating as agreed with the NHS Genomic Medicine Service.
Embryonal tumour of possible germline origin v0.2 KRAS Achchuthan Shanmugasundram reviewed gene: KRAS: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: RAS-associated autoimmune leukoproliferative disorder, OMIM:614470, cardiofaciocutaneous syndrome 2, MONDO:0014112, Cardiofaciocutaneous syndrome 2, OMIM:615278, Noonan syndrome 3, OMIM:609942, Noonan syndrome 3, MONDO:0012371; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Embryonal tumour of possible germline origin v0.1 KRAS Achchuthan Shanmugasundram gene: KRAS was added
gene: KRAS was added to Embryonal tumour of possible germline origin. Sources: NHS GMS,Expert Review Green
Mode of inheritance for gene: KRAS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene: KRAS were set to Noonan syndrome 3, MONDO:0012371; cardiofaciocutaneous syndrome 2, MONDO:0014112; Cardiofaciocutaneous syndrome 2, OMIM:615278; RAS-associated autoimmune leukoproliferative disorder, OMIM:614470; Noonan syndrome 3, OMIM:609942