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Primary immunodeficiency or monogenic inflammatory bowel disease v2.455 LAMTOR2 Arina Puzriakova Classified gene: LAMTOR2 as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.455 LAMTOR2 Arina Puzriakova Added comment: Comment on list classification: Gene was reassessed following a recent Amber review by Zornitza Stark. Although there has only been one family reported to date, the rating was based on multiple Green GMS expert reviews as the functional support was deemed sufficiently compelling. Therefore, the Green gene rating will be maintained on this panel.
Primary immunodeficiency or monogenic inflammatory bowel disease v2.455 LAMTOR2 Arina Puzriakova Gene: lamtor2 has been classified as Green List (High Evidence).
Primary immunodeficiency or monogenic inflammatory bowel disease v2.452 LAMTOR2 Zornitza Stark reviewed gene: LAMTOR2: Rating: AMBER; Mode of pathogenicity: None; Publications: 17195838, 24092934; Phenotypes: Immunodeficiency due to defect in MAPBP-interacting protein, MIM# 610798; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LAMTOR2 Louise Daugherty commented on gene: LAMTOR2: Gene rating submitted by Kimberly Gilmour and Austen Worth on behalf of London North GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email 6th September the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LAMTOR2 Louise Daugherty commented on gene: LAMTOR2: Gene rating submitted by Tracy Briggs, David Gokhale and Abigal Rousseau on behalf of North West GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email on 20th June the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LAMTOR2 Kimberly Gilmour reviewed gene: LAMTOR2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 LAMTOR2 Tracy Briggs reviewed gene: LAMTOR2: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.60 LAMTOR2 Louise Daugherty Source NHS GMS was added to LAMTOR2.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.59 LAMTOR2 Louise Daugherty Source North West GLH was added to LAMTOR2.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.58 LAMTOR2 Louise Daugherty Source London North GLH was added to LAMTOR2.
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty marked gene: LAMTOR2 as ready
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty commented on gene: LAMTOR2
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty edited their review of gene: LAMTOR2
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty marked gene: LAMTOR2 as ready
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty classified LAMTOR2 as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Sophie Hambleton reviewed gene: LAMTOR2
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty commented on LAMTOR2
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty commented on LAMTOR2
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty commented on LAMTOR2
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty reviewed LAMTOR2
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty Added gene to panel
Primary immunodeficiency or monogenic inflammatory bowel disease LAMTOR2 Louise Daugherty Added gene to panel