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| COVID-19 research v0.36 | MCM4 |
Ellen McDonagh gene: MCM4 was added gene: MCM4 was added to Viral susceptibility. Sources: Expert Review Green,ESID Registry 20171117,North West GLH,Victorian Clinical Genetics Services,GRID V2.0,NHS GMS,London North GLH,IUIS Classification February 2018 Mode of inheritance for gene: MCM4 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: MCM4 were set to 22354167; 22499342; 22354170; 16532402 Phenotypes for gene: MCM4 were set to Combined immunodeficiencies with associated or syndromic features; Predisposition to several viral infection; Immunodeficiency 54, 609981; MCM4 deficiency; NK cells: low number and function. Viral infections (EBV, HSV, VZV), short stature, B cell lymphoma, adrenal failure; Natural killer cell and glucocorticoid deficiency with DNA repair defect |
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