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DDG2P v6.249 MFN2 Achchuthan Shanmugasundram Mode of pathogenicity for gene: MFN2 was changed from Other to None
DDG2P v6.17 MFN2 Achchuthan Shanmugasundram commented on gene: MFN2: The DDG2P confidence category, allelic requirement and molecular mechanism for MFN2-related developmental disorder are moderate, monoallelic_autosomal and undetermined (PMID:33057194). The cross-cutting modifier is potential secondary finding. More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P03015.
DDG2P v3.12 MFN2 Achchuthan Shanmugasundram reviewed gene: MFN2: Rating: GREEN; Mode of pathogenicity: Other; Publications: 33057194; Phenotypes: MFN2-related developmental disorder; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
DDG2P v3.11 MFN2 Achchuthan Shanmugasundram gene: MFN2 was added
gene: MFN2 was added to DDG2P. Sources: Expert Review Green,DD-Gene2Phenotype
Mode of inheritance for gene: MFN2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Publications for gene: MFN2 were set to 33057194
Phenotypes for gene: MFN2 were set to MFN2-related developmental disorder
Mode of pathogenicity for gene: MFN2 was set to Other