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Paediatric pseudo-obstruction syndrome v2.7 MT-TL1 Katherine Schon gene: MT-TL1 was added
gene: MT-TL1 was added to Paediatric pseudo-obstruction syndrome. Sources: Literature
Mode of inheritance for gene gene: MT-TL1 was set to MITOCHONDRIAL
Publications for gene: MT-TL1 were set to PMID: 27453452; 42024134; 28458318
Phenotypes for gene: MT-TL1 were set to Intestinal pseudo-obstruction HP:0004389
Penetrance for gene: MT-TL1 were set to Incomplete
Mode of pathogenicity for gene: MT-TL1 was set to Other
Review for gene: MT-TL1 was set to GREEN
Added comment: Intestinal pseudo-obstruction is observed as one of the phenotypes of the multi-system mitochondrial disease associated with the m.3243A>G pathogenic variant.
Sources: Literature