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Fetal anomalies v5.80 MYBBP1A Achchuthan Shanmugasundram Tag gene-checked tag was added to gene: MYBBP1A.
Fetal anomalies v5.78 MYBBP1A Achchuthan Shanmugasundram Tag Q3_24_promote_green was removed from gene: MYBBP1A.
Tag Q3_24_NHS_review was removed from gene: MYBBP1A.
Fetal anomalies v5.78 MYBBP1A Achchuthan Shanmugasundram reviewed gene: MYBBP1A: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Fetal anomalies v5.77 MYBBP1A Achchuthan Shanmugasundram Source NHS GMS was added to MYBBP1A.
Source Expert Review Green was added to MYBBP1A.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Fetal anomalies v5.2 MYBBP1A Achchuthan Shanmugasundram Phenotypes for gene: MYBBP1A were changed from to non-immune hydrops fetalis, MONDO:0009369
Fetal anomalies v5.1 MYBBP1A Achchuthan Shanmugasundram Tag Q3_24_MOI was removed from gene: MYBBP1A.
Fetal anomalies v4.190 MYBBP1A Sarah Leigh Classified gene: MYBBP1A as Amber List (moderate evidence)
Fetal anomalies v4.190 MYBBP1A Sarah Leigh Added comment: Comment on list classification: There is enough information for this gene to be green on this panel.
Fetal anomalies v4.190 MYBBP1A Sarah Leigh Gene: mybbp1a has been classified as Amber List (Moderate Evidence).
Fetal anomalies v4.189 MYBBP1A Sarah Leigh Tag Q3_24_NHS_review tag was added to gene: MYBBP1A.
Tag Q3_24_MOI tag was added to gene: MYBBP1A.
Fetal anomalies v4.189 MYBBP1A Sarah Leigh Tag Q3_24_promote_green tag was added to gene: MYBBP1A.
Fetal anomalies v4.189 MYBBP1A Sarah Leigh reviewed gene: MYBBP1A: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Non-immune hydrops fetalis; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Fetal anomalies v4.189 MYBBP1A Sarah Leigh Classified gene: MYBBP1A as Amber List (moderate evidence)
Fetal anomalies v4.189 MYBBP1A Sarah Leigh Gene: mybbp1a has been classified as Amber List (Moderate Evidence).
Fetal anomalies v4.188 MYBBP1A Sarah Graham gene: MYBBP1A was added
gene: MYBBP1A was added to Fetal anomalies. Sources: Literature
Mode of inheritance for gene: MYBBP1A was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: MYBBP1A were set to 39191491; 28425981
Review for gene: MYBBP1A was set to GREEN
Added comment: Three fetuses have been reported with biallelic variants in MYBBP1A in association with oligohydramnios, cystic hygroma, pleural effusion, generalized hydrops, ascites, severe IUGR and skeletal anomalies (PMID 39191491;28425981).
Sources: Literature