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Dilated and arrhythmogenic cardiomyopathy v3.2 PRDM16 Jesse Hayesmoore reviewed gene: PRDM16: Rating: GREEN; Mode of pathogenicity: None; Publications: PMID: 23768516, PMID: 24454898, PMID: 37395136, PMID: 33500567, PMID: 29367541, PMID: 35893073, PMID: 29447731, PMID: 30847666, PMID: 33082984, PMID: 32183154, PMID: 34540771, PMID: 34350506, PMID: 34935411, PMID: 38113297, PMID: 31965688, PMID: 40935858, PMID: 21343612, PMID: 32083975, PMID: 33086060, PMID: 34915728; Phenotypes: LVNC, DCM; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted; Current diagnostic: yes
Dilated and arrhythmogenic cardiomyopathy v2.36 PRDM16 Eleanor Williams Tag Q2_24_promote_green was removed from gene: PRDM16.
Tag Q2_24_NHS_review was removed from gene: PRDM16.
Dilated and arrhythmogenic cardiomyopathy v2.35 PRDM16 Eleanor Williams reviewed gene: PRDM16: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Dilated and arrhythmogenic cardiomyopathy v2.34 PRDM16 Eleanor Williams Source Expert Review Green was added to PRDM16.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Dilated and arrhythmogenic cardiomyopathy v2.29 PRDM16 Sarah Leigh Tag Q2_24_promote_green tag was added to gene: PRDM16.
Tag Q2_24_NHS_review tag was added to gene: PRDM16.
Dilated and arrhythmogenic cardiomyopathy v2.29 PRDM16 Sarah Leigh reviewed gene: PRDM16: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None
Dilated and arrhythmogenic cardiomyopathy v2.29 PRDM16 Sarah Leigh Phenotypes for gene: PRDM16 were changed from to Cardiomyopathy, dilated, 1LL, OMIM:615373; Left ventricular noncompaction 8, OMIM:615373; left ventricular noncompaction 8, MONDO:0014152
Dilated and arrhythmogenic cardiomyopathy v2.28 PRDM16 Sarah Leigh Publications for gene: PRDM16 were set to
Dilated and arrhythmogenic cardiomyopathy v2.25 PRDM16 Mike Spiller reviewed gene: PRDM16: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Dilated and arrhythmogenic cardiomyopathy v0.52 PRDM16 Ivone Leong reviewed gene: PRDM16: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Dilated and arrhythmogenic cardiomyopathy v0.51 PRDM16 Ivone Leong gene: PRDM16 was added
gene: PRDM16 was added to Dilated cardiomyopathy - adult and teen. Sources: NHS GMS,Expert Review Amber
Mode of inheritance for gene: PRDM16 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown