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DDG2P v6.308 PSMC3 Achchuthan Shanmugasundram Mode of pathogenicity for gene: PSMC3 was changed from Other to None
DDG2P v6.17 PSMC3 Achchuthan Shanmugasundram Tag de novo tag was added to gene: PSMC3.
DDG2P v6.17 PSMC3 Achchuthan Shanmugasundram edited their review of gene: PSMC3: Added comment: The DDG2P confidence category, allelic requirement and molecular mechanism for PSMC3-related neurodevelopmental disorder are moderate, monoallelic_autosomal and undetermined (PMID:37256937). The cross-cutting modifier is restricted mutation set. More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P03496.; Changed phenotypes to: MONDO:0700092, PSMC3-related neurodevelopmental disorder
DDG2P v4.10 PSMC3 Achchuthan Shanmugasundram reviewed gene: PSMC3: Rating: GREEN; Mode of pathogenicity: Other; Publications: 37256937; Phenotypes: PSMC3-related neurodevelopmental disorder; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
DDG2P v4.9 PSMC3 Achchuthan Shanmugasundram gene: PSMC3 was added
gene: PSMC3 was added to DDG2P. Sources: Expert Review Green,DD-Gene2Phenotype
Mode of inheritance for gene: PSMC3 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Publications for gene: PSMC3 were set to 37256937
Phenotypes for gene: PSMC3 were set to PSMC3-related neurodevelopmental disorder
Mode of pathogenicity for gene: PSMC3 was set to Other