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Breast cancer pertinent cancer susceptibility v2.17 PTEN Achchuthan Shanmugasundram Tag Q2_25_ promote_green was removed from gene: PTEN.
Tag Q2_25_expert_review was removed from gene: PTEN.
Breast cancer pertinent cancer susceptibility v2.17 PTEN Achchuthan Shanmugasundram changed review comment from: After NHS Genomic Medicine Service consideration, the rating of this gene has not been changed and remains red. The GMS reviewers note that there are no clinical guidelines to manage the findings.; to: After NHS Genomic Medicine Service consideration, the rating of this gene has not been changed and remains amber. The GMS reviewers note that there are no clinical guidelines to manage the findings.
Breast cancer pertinent cancer susceptibility v2.17 PTEN Achchuthan Shanmugasundram commented on gene: PTEN
Breast cancer pertinent cancer susceptibility v2.15 PTEN Arina Puzriakova Classified gene: PTEN as Amber List (moderate evidence)
Breast cancer pertinent cancer susceptibility v2.15 PTEN Arina Puzriakova Gene: pten has been classified as Amber List (Moderate Evidence).
Breast cancer pertinent cancer susceptibility v2.13 PTEN Arina Puzriakova Classified gene: PTEN as Red List (low evidence)
Breast cancer pertinent cancer susceptibility v2.13 PTEN Arina Puzriakova Added comment: Comment on list classification: Germline PTEN variants confer up to 85% lifetime risk of female breast cancer. Inclusion on this panel should therefore be reviewed by the expert group at the next GMS panel update.
Breast cancer pertinent cancer susceptibility v2.13 PTEN Arina Puzriakova Gene: pten has been classified as Red List (Low Evidence).
Breast cancer pertinent cancer susceptibility v2.12 PTEN Arina Puzriakova Tag Q2_25_ promote_green tag was added to gene: PTEN.
Tag Q2_25_expert_review tag was added to gene: PTEN.
Breast cancer pertinent cancer susceptibility v2.8 PTEN Dmitrijs Rots reviewed gene: PTEN: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: PHTS; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Breast cancer pertinent cancer susceptibility v1.1 PTEN Catherine Snow Classified gene: PTEN as Red List (low evidence)
Breast cancer pertinent cancer susceptibility v1.1 PTEN Catherine Snow Added comment: Comment on list classification: Rating red following review by C Turnball (ICR) of predisposition panels for GMS phase 2 indications.
Breast cancer pertinent cancer susceptibility v1.1 PTEN Catherine Snow Gene: pten has been classified as Red List (Low Evidence).
Breast cancer pertinent cancer susceptibility PTEN Ellen McDonagh classified PTEN as green
Breast cancer pertinent cancer susceptibility PTEN Ellen McDonagh commented on PTEN