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Mitochondrial disorders v6.4 QARS Achchuthan Shanmugasundram Tag Q3_23_promote_green was removed from gene: QARS.
Mitochondrial disorders v6.4 QARS Sarah Leigh edited their review of gene: QARS: Changed rating: GREEN
Mitochondrial disorders v6.3 QARS Sarah Leigh reviewed gene: QARS: Rating: ; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Mitochondrial disorders v6.2 QARS Achchuthan Shanmugasundram Source NHS GMS was added to QARS.
Source Expert Review Green was added to QARS.
Rating Changed from Amber List (moderate evidence) to Green List (high evidence)
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram changed review comment from: Comment on list classification: As reviewed by Zornitza Stark, QARS should be included in this panel with green rating in the next GMS review in line with other t-RNA synthetases.; to: Comment on list classification: As reviewed by Zornitza Stark, QARS should be included in this panel with green rating in line with other t-RNA synthetases.
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram Deleted their comment
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram Classified gene: QARS as Amber List (moderate evidence)
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram Added comment: Comment on list classification: As reviewed by Zornitza Stark, QARS should be included in this panel with green rating in the next GMS review in line with other t-RNA synthetases.
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram Gene: qars has been classified as Amber List (Moderate Evidence).
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram Classified gene: QARS as Amber List (moderate evidence)
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram Added comment: Comment on list classification: As reviewed by Zornitza Stark, QARS should be included in this panel with green rating in the next GMS review in line with other t-RNA synthetases.
Mitochondrial disorders v4.82 QARS Achchuthan Shanmugasundram Gene: qars has been classified as Amber List (Moderate Evidence).
Mitochondrial disorders v4.81 QARS Achchuthan Shanmugasundram Tag Q3_23_promote_green tag was added to gene: QARS.
Mitochondrial disorders v4.81 QARS Achchuthan Shanmugasundram Phenotypes for gene: QARS were changed from Multiple respiratory chain complex deficiencies (disorders of protein synthesis) to Microcephaly, progressive, seizures, and cerebral and cerebellar atrophy, OMIM:615760; Multiple respiratory chain complex deficiencies (disorders of protein synthesis)
Mitochondrial disorders v4.80 QARS Achchuthan Shanmugasundram Publications for gene: QARS were set to
Mitochondrial disorders v4.79 QARS Achchuthan Shanmugasundram Mode of inheritance for gene: QARS was changed from to BIALLELIC, autosomal or pseudoautosomal
Mitochondrial disorders v4.78 QARS Achchuthan Shanmugasundram reviewed gene: QARS: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Microcephaly, progressive, seizures, and cerebral and cerebellar atrophy, OMIM:615760; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Mitochondrial disorders v2.5 QARS Zornitza Stark edited their review of gene: QARS: Added comment: Encodes t-RNA synthetase, over 20 individuals reported, include in mito panel in line with other t-RNA synthetases.; Changed rating: GREEN; Changed publications: 28620870, 25471517, 25432320, 25041233, 24656866, 32042906; Changed phenotypes: Microcephaly, progressive, seizures, and cerebral and cerebellar atrophy, MIM# 615760
Mitochondrial disorders v1.485 QARS Louise Daugherty Tag new-gene-name tag was added to gene: QARS.
Mitochondrial disorders v1.485 QARS Louise Daugherty commented on gene: QARS
Mitochondrial disorders QARS Zornitza Stark reviewed gene: QARS