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Date	Panel	Item	Activity
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08 Dec 2022	IUGR and IGF abnormalities v1.55	SHOX	Arina Puzriakova Phenotypes for gene: SHOX were changed from to Langer mesomelic dysplasia, OMIM:249700 (PR); Leri-Weill dyschondrosteosis, OMIM:127300 (PD); Short stature, idiopathic familial, OMIM:300582
04 Nov 2021	IUGR and IGF abnormalities v1.41	SHOX	Ivone Leong Tag Pseudoautosomal region 1 tag was added to gene: SHOX.
12 Dec 2019	IUGR and IGF abnormalities v1.30	SHOX	Eleanor Williams Added comment: Comment on mode of inheritance: Updating mode of inheritance as monoallelic cases tend to be milder e.g. familial short stature / Leri-Weill, whereas biallelic are more severe (Langer mesomelic dysplasia).
12 Dec 2019	IUGR and IGF abnormalities v1.30	SHOX	Eleanor Williams Mode of inheritance for gene: SHOX was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal