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DDG2P v6.337 SIAH1 Achchuthan Shanmugasundram Mode of pathogenicity for gene: SIAH1 was changed from Other to None
DDG2P v6.17 SIAH1 Achchuthan Shanmugasundram edited their review of gene: SIAH1: Added comment: The DDG2P confidence category, allelic requirement and molecular mechanism for SIAH1-related neurodevelopmental disorder are strong, monoallelic_autosomal and undetermined (PMID:32430360). More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P02959.; Changed phenotypes to: SIAH1-related neurodevelopmental disorder, MONDO:0859144, OMIM:619314.0, SIAH1-associated neurodevelopmental disorder
DDG2P v3.12 SIAH1 Achchuthan Shanmugasundram reviewed gene: SIAH1: Rating: GREEN; Mode of pathogenicity: Other; Publications: 32430360; Phenotypes: SIAH1-associated neurodevelopmental disorder; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
DDG2P v3.11 SIAH1 Achchuthan Shanmugasundram gene: SIAH1 was added
gene: SIAH1 was added to DDG2P. Sources: Expert Review Green,DD-Gene2Phenotype
Mode of inheritance for gene: SIAH1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Publications for gene: SIAH1 were set to 32430360
Phenotypes for gene: SIAH1 were set to SIAH1-associated neurodevelopmental disorder
Mode of pathogenicity for gene: SIAH1 was set to Other