Activity
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4 actions
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| DDG2P v6.358 | SOS2 | Achchuthan Shanmugasundram Mode of pathogenicity for gene: SOS2 was changed from Other to None | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v6.17 | SOS2 | Achchuthan Shanmugasundram edited their review of gene: SOS2: Added comment: The DDG2P confidence category, allelic requirement and molecular mechanism for SOS2-related Noonan syndrome are definitive, monoallelic_autosomal and undetermined (PMIDs: 25795793, 26173643, 32788663). More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P03139.; Changed phenotypes to: SOS2-related Noonan syndrome, OMIM:616559.0, MONDO:0014691, SOS-2 associated Noonan syndrome, OMIM:616559 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v3.12 | SOS2 | Achchuthan Shanmugasundram reviewed gene: SOS2: Rating: GREEN; Mode of pathogenicity: Other; Publications: 26173643, 25795793, 32788663; Phenotypes: SOS-2 associated Noonan syndrome, OMIM:616559; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v3.11 | SOS2 |
Achchuthan Shanmugasundram gene: SOS2 was added gene: SOS2 was added to DDG2P. Sources: Expert Review Green,DD-Gene2Phenotype Mode of inheritance for gene: SOS2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: SOS2 were set to 26173643; 25795793; 32788663 Phenotypes for gene: SOS2 were set to SOS-2 associated Noonan syndrome, OMIM:616559 Mode of pathogenicity for gene: SOS2 was set to Other |
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