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Primary immunodeficiency or monogenic inflammatory bowel disease v2.314 STAT3 Eleanor Williams Classified gene: STAT3 as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.314 STAT3 Eleanor Williams Added comment: Comment on list classification: Changed rating of gene from Red to Green. This gene was rated as Green in v2.208 and incorrectly automatically demoted to Red in v2.209. This was due to a defect in the automatic PanelApp uploading tool when a set of publications was added to the panel with the source ‘Other’, and under certain conditions associated to previous sources listed, resulted in the rating of the gene being automatically changed when it should not have been.
Primary immunodeficiency or monogenic inflammatory bowel disease v2.314 STAT3 Eleanor Williams Gene: stat3 has been classified as Green List (High Evidence).
Primary immunodeficiency or monogenic inflammatory bowel disease v2.209 STAT3 Eleanor Williams Source Other was added to STAT3.
Publications for gene STAT3 were updated from 17676033; 17881745; 25038750; 25359994 to 28402852; 25349174; 17881745; 17676033; 25359994; 25038750
Rating Changed from Green List (high evidence) to Red List (low evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease v2.208 STAT3 Eleanor Williams edited their review of gene: STAT3: Added comment: The following PubMed IDs were added to entity STAT3: 25349174;28402852;25359994;25038750. These publications have been associated with OMIM phenotype MIM#615952, which is listed for this entity, by the immunedysregulation subgroup of the Human Phenotype Ontology Immune Mediated Disorders Consortium (https://hpo-immune-mediated-disorders.groups.io/g/update) in August 2020.; Changed publications: 25349174, 28402852, 25359994, 25038750
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 STAT3 Louise Daugherty commented on gene: STAT3: Gene rating submitted by Kimberly Gilmour and Austen Worth on behalf of London North GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email 6th September the Specialist Test Group all agreed there is enough evidence to rate this gene Green.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 STAT3 Louise Daugherty edited their review of gene: STAT3: Added comment: Gene rating submitted by Tracy Briggs, David Gokhale and Abigal Rousseau on behalf of North West GLH for the GMS Immunology specialist test group. As discussed with the GMS Immunology Specialist Test Group during webex call 28th March 2019 and confirmed in follow up email on 20th June the Specialist Test Group all agreed there is enough evidence to rate this gene Green.; Changed rating: GREEN
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 STAT3 Kimberly Gilmour reviewed gene: STAT3: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.94 STAT3 Tracy Briggs reviewed gene: STAT3: Rating: GREEN; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance:
Primary immunodeficiency or monogenic inflammatory bowel disease v1.60 STAT3 Louise Daugherty Source NHS GMS was added to STAT3.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.59 STAT3 Louise Daugherty Source North West GLH was added to STAT3.
Primary immunodeficiency or monogenic inflammatory bowel disease v1.58 STAT3 Louise Daugherty Source London North GLH was added to STAT3.
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty commented on gene: STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty marked gene: STAT3 as ready
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Sophie Hambleton reviewed gene: STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Eleanor Williams edited their review of STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Eleanor Williams edited their review of STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Eleanor Williams edited their review of STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Eleanor Williams classified STAT3 as Green List (high evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty classified STAT3 as Amber List (moderate evidence)
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty commented on STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty commented on STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty commented on STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty reviewed STAT3
Primary immunodeficiency or monogenic inflammatory bowel disease STAT3 Louise Daugherty Added gene to panel