Activity
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6 actions
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| DDG2P v6.373 | TACR3 | Achchuthan Shanmugasundram Mode of pathogenicity for gene: TACR3 was changed from Other to None | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v6.17 | TACR3 | Achchuthan Shanmugasundram edited their review of gene: TACR3: Added comment: The DDG2P confidence category, allelic requirement and molecular mechanism for TACR3-related hypogonadotropic hypogonadism are strong, biallelic_autosomal and undetermined (PMID:19079066). More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P00493.; Changed phenotypes to: HYPOGONADOTROPIC HYPOGONADISM, OMIM:146110, MONDO:0013913, OMIM:614840.0, TACR3-related hypogonadotropic hypogonadism | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v3.12 | TACR3 | Achchuthan Shanmugasundram reviewed gene: TACR3: Rating: GREEN; Mode of pathogenicity: Other; Publications: 19079066; Phenotypes: HYPOGONADOTROPIC HYPOGONADISM, OMIM:146110; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v3.11 | TACR3 |
Achchuthan Shanmugasundram Source Expert Review Green was added to TACR3. Mode of pathogenicity for gene TACR3 was changed from Other - please provide details in the comments to Other Rating Changed from Amber List (moderate evidence) to Green List (high evidence) |
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| DDG2P v0.2 | TACR3 | Rebecca Foulger reviewed gene: TACR3: Rating: AMBER; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DDG2P v0.1 | TACR3 |
Rebecca Foulger gene: TACR3 was added gene: TACR3 was added to DDG2P. Sources: Expert Review Amber,DD-Gene2Phenotype Mode of inheritance for gene: TACR3 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: TACR3 were set to 19079066 Phenotypes for gene: TACR3 were set to HYPOGONADOTROPIC HYPOGONADISM 146110 Mode of pathogenicity for gene: TACR3 was set to Other - please provide details in the comments |
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