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Limb disorders v0.208 TBX22 Rebecca Foulger Marked gene: TBX22 as ready
Limb disorders v0.208 TBX22 Rebecca Foulger Gene: tbx22 has been classified as Red List (Low Evidence).
Limb disorders v0.208 TBX22 Rebecca Foulger Publications for gene: TBX22 were set to 21375406; 839509
Limb disorders v0.207 TBX22 Rebecca Foulger Classified gene: TBX22 as Red List (low evidence)
Limb disorders v0.207 TBX22 Rebecca Foulger Added comment: Comment on list classification: Kept rating as Red: there is some evidence linking limb anomalies to TBX22 variants (PMID:21375406) but currently insufficient cases for inclusion on a diagnostic panel.
Limb disorders v0.207 TBX22 Rebecca Foulger Gene: tbx22 has been classified as Red List (Low Evidence).
Limb disorders v0.206 TBX22 Rebecca Foulger commented on gene: TBX22: Abruzzo-Erickson syndrome (MIM:302905, reported by Abruzzo and Erickson in 1977, PMID:839509) includes radial synostosis (an abnormal connection (synostosis) of the radius and ulna (bones in the forearm) at birth).
Limb disorders v0.206 TBX22 Rebecca Foulger Publications for gene: TBX22 were set to
Limb disorders v0.205 TBX22 Rebecca Foulger commented on gene: TBX22
Limb disorders v0.205 TBX22 Rebecca Foulger Phenotypes for gene: TBX22 were changed from Polydactyly; ?Abruzzo-Erickson syndrome, 302905; Cleft palate with ankyloglossia, 303400; Radioulnar synostosis to Polydactyly; ?Abruzzo-Erickson syndrome, 302905; Cleft palate with ankyloglossia, 303400; Radioulnar synostosis; upper limb anomalies; clinodactyly
Limb disorders v0.204 TBX22 Rebecca Foulger Phenotypes for gene: TBX22 were changed from Polydactyly to Polydactyly; ?Abruzzo-Erickson syndrome, 302905; Cleft palate with ankyloglossia, 303400; Radioulnar synostosis
Limb disorders v0.203 TBX22 Rebecca Foulger Mode of inheritance for gene: TBX22 was changed from to X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Limb disorders TBX22 Ellen McDonagh Added gene to panel