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DDG2P v6.387 TRA2B Achchuthan Shanmugasundram Mode of pathogenicity for gene: TRA2B was changed from Other to None
DDG2P v6.17 TRA2B Achchuthan Shanmugasundram edited their review of gene: TRA2B: Added comment: The DDG2P confidence category, allelic requirement and molecular mechanism for TRA2B-related neurodevelopmental syndrome are moderate, monoallelic_autosomal and undetermined (PMID:36549593). The cross-cutting modifier is restricted mutation set. More details can be found in https://www.ebi.ac.uk/gene2phenotype/lgd/G2P03418.; Changed phenotypes to: MONDO:0700092, TRA2B-related neurodevelopmental syndrome, TRA2B-associated neurodevelopmental syndrome
DDG2P v3.73 TRA2B Eleanor Williams commented on gene: TRA2B
DDG2P v3.73 TRA2B Eleanor Williams Tag gene-checked tag was added to gene: TRA2B.
DDG2P v3.12 TRA2B Achchuthan Shanmugasundram reviewed gene: TRA2B: Rating: GREEN; Mode of pathogenicity: Other; Publications: 36549593; Phenotypes: TRA2B-associated neurodevelopmental syndrome; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
DDG2P v3.11 TRA2B Achchuthan Shanmugasundram gene: TRA2B was added
gene: TRA2B was added to DDG2P. Sources: Expert Review Green,DD-Gene2Phenotype
Mode of inheritance for gene: TRA2B was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Publications for gene: TRA2B were set to 36549593
Phenotypes for gene: TRA2B were set to TRA2B-associated neurodevelopmental syndrome
Mode of pathogenicity for gene: TRA2B was set to Other