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Osteopetrosis v1.37 TYROBP Eleanor Williams Tag Q3_24_NHS_review was removed from gene: TYROBP.
Tag Q3_24_demote_red was removed from gene: TYROBP.
Tag Q3_24_expert_review was removed from gene: TYROBP.
Osteopetrosis v1.37 TYROBP Eleanor Williams edited their review of gene: TYROBP: Added comment: The rating of this gene has been updated to red following NHS Genomic Medicine Service approval.; Changed rating: RED
Osteopetrosis v1.36 TYROBP Eleanor Williams Source Expert Review Red was added to TYROBP.
Rating Changed from Green List (high evidence) to Red List (low evidence)
Osteopetrosis v1.34 TYROBP Sarah Leigh Tag Q3_24_NHS_review tag was added to gene: TYROBP.
Tag Q3_24_demote_red tag was added to gene: TYROBP.
Tag Q3_24_expert_review tag was added to gene: TYROBP.
Osteopetrosis v1.34 TYROBP Sarah Leigh reviewed gene: TYROBP: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: None
Osteopetrosis v1.34 TYROBP Ian Berry reviewed gene: TYROBP: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Osteopetrosis v1.24 TYROBP Eleanor Williams Phenotypes for gene: TYROBP were changed from Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1 221770 to Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1 OMIM:221770
Osteopetrosis v0.3 TYROBP Eleanor Williams commented on gene: TYROBP
Osteopetrosis v0.1 TYROBP Catherine Snow gene: TYROBP was added
gene: TYROBP was added to Osteopetrosis. Sources: Expert Review Green,NHS GMS
Mode of inheritance for gene: TYROBP was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: TYROBP were set to Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1 221770