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Primary ciliary disorders v1.45 WFDC2 Arina Puzriakova Publications for gene: WFDC2 were set to 38626355
Primary ciliary disorders v1.44 WFDC2 Arina Puzriakova Classified gene: WFDC2 as Red List (low evidence)
Primary ciliary disorders v1.44 WFDC2 Arina Puzriakova Added comment: Comment on list classification: PMID: 38626355; 4040104214 - individuals from 14 families have been reported with biallelic variants in this gene and bronchiectasis, nasal polyposis and sinopulmonary disease. Ciliary structure, beat frequency and coordination, as well as mucus viscosity were all within normal range and therefore this gene does not seem relevant to this panel. Rating Red.
Primary ciliary disorders v1.44 WFDC2 Arina Puzriakova Gene: wfdc2 has been classified as Red List (Low Evidence).
Primary ciliary disorders v1.43 WFDC2 Arina Puzriakova Phenotypes for gene: WFDC2 were changed from Nasal Polyposis; Bronchiectasis to Bronchiectasis and nasal polyposis, OMIM:620984
Primary ciliary disorders v1.42 WFDC2 Max Xiaohang Zhao gene: WFDC2 was added
gene: WFDC2 was added to Primary ciliary disorders. Sources: Literature
Mode of inheritance for gene: WFDC2 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: WFDC2 were set to 38626355
Phenotypes for gene: WFDC2 were set to Nasal Polyposis; Bronchiectasis
Penetrance for gene: WFDC2 were set to unknown
Review for gene: WFDC2 was set to RED
gene: WFDC2 was marked as current diagnostic
Added comment: Sources: Literature