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APC associated Polyposis v1.2 APC Achchuthan Shanmugasundram Added comment: Comment on phenotypes: This gene has been associated with relevant phenotypes in OMIM (MIMs #135290, #175100 & #619182) and these OMIM records were last accessed on 17 December 2025.
APC associated Polyposis v1.2 APC Achchuthan Shanmugasundram Phenotypes for gene: APC were changed from to Desmoid disease, hereditary, OMIM:135290; Adenomatous polyposis coli, OMIM:175100; Brain tumor-polyposis syndrome 2, OMIM:175100; Gardner syndrome, OMIM:175100; Gastric adenocarcinoma and proximal polyposis of the stomach, OMIM:619182; desmoid tumor, MONDO:0007608; gastric adenocarcinoma and proximal polyposis of the stomach, MONDO:0017790; familial adenomatous polyposis 1, MONDO:0021056
APC associated Polyposis v1.1 Achchuthan Shanmugasundram Panel version 1.0 has been signed off on 2023-09-14
APC associated Polyposis v1.0 Achchuthan Shanmugasundram promoted panel to version 1.0
APC associated Polyposis v0.10 Achchuthan Shanmugasundram Panel types changed to GMS Rare Disease; GMS signed-off
APC associated Polyposis v0.9 Achchuthan Shanmugasundram Panel status changed from internal to public
APC associated Polyposis v0.8 Achchuthan Shanmugasundram Panel types changed to GMS Rare Disease
APC associated Polyposis v0.7 Eleanor Williams Panel status changed from public to internal
APC associated Polyposis v0.6 Eleanor Williams Panel status changed from internal to public
Panel types changed to
APC associated Polyposis v0.5 APC Eleanor Williams changed review comment from: APC has been added to the panel for R414 APC associated Polyposis with a green rating as agreed with the NHS Genomic Medicine Service.; to: APC has been added to the panel for the clinical indication 'R414 APC associated Polyposis' with a green rating as agreed with the NHS Genomic Medicine Service.
APC associated Polyposis v0.5 APC Eleanor Williams reviewed gene: APC: Rating: ; Mode of pathogenicity: ; Publications: ; Phenotypes: ; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
APC associated Polyposis v0.4 APC Eleanor Williams gene: APC was added
gene: APC was added to APC associated Polyposis. Sources: Expert Review Green,NHS GMS
Mode of inheritance for gene: APC was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
APC associated Polyposis v0.1 Eleanor Williams Panel types changed to GMS Rare Disease
APC associated Polyposis v0.0 Eleanor Williams Added Panel APC associated Polyposis
Set list of related panels to R414