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Lysosomal acid lipase deficiency v1.2 LIPA Achchuthan Shanmugasundram Added comment: Comment on phenotypes: This gene has been associated with relevant phenotypes in OMIM (MIMs #278000 & #620151) and the OMIM records were last accessed on 20 December 2025.
Lysosomal acid lipase deficiency v1.2 LIPA Achchuthan Shanmugasundram Phenotypes for gene: LIPA were changed from to Cholesteryl ester storage disease, OMIM:278000; Wolman disease, OMIM:620151; Wolman disease, MONDO:0019148; cholesteryl ester storage disease, MONDO:0019149
Lysosomal acid lipase deficiency v1.1 Sarah Leigh Panel version 1.0 has been signed off on 2023-09-14
Lysosomal acid lipase deficiency v1.0 Sarah Leigh promoted panel to version 1.0
Lysosomal acid lipase deficiency v0.3 Sarah Leigh Panel types changed to GMS Rare Disease; GMS signed-off
Lysosomal acid lipase deficiency v0.2 Achchuthan Shanmugasundram Panel status changed from internal to public
Lysosomal acid lipase deficiency v0.1 LIPA Achchuthan Shanmugasundram reviewed gene: LIPA: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Lysosomal acid lipase deficiency v0.1 LIPA Achchuthan Shanmugasundram gene: LIPA was added
gene: LIPA was added to Lysosomal acid lipase deficiency. Sources: Expert Review Green,NHS GMS
Mode of inheritance for gene: LIPA was set to BIALLELIC, autosomal or pseudoautosomal
Lysosomal acid lipase deficiency v0.0 Achchuthan Shanmugasundram Added Panel Lysosomal acid lipase deficiency
Set list of related panels to R325
Set panel types to: GMS Rare Disease