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Neuronal ceroid lipofuscinosis type 2 v1.2 TPP1 Achchuthan Shanmugasundram Added comment: Comment on phenotypes: This gene has been associated with relevant phenotypes in OMIM (MIM #204500) and the OMIM record was last accessed on 29 December 2025.
Neuronal ceroid lipofuscinosis type 2 v1.2 TPP1 Achchuthan Shanmugasundram Phenotypes for gene: TPP1 were changed from to Ceroid lipofuscinosis, neuronal, 2, OMIM:204500; neuronal ceroid lipofuscinosis 2, MONDO:0008769
Neuronal ceroid lipofuscinosis type 2 v1.1 Sarah Leigh Panel version 1.0 has been signed off on 2023-09-14
Neuronal ceroid lipofuscinosis type 2 v1.0 Sarah Leigh promoted panel to version 1.0
Neuronal ceroid lipofuscinosis type 2 v0.3 Sarah Leigh Panel types changed to GMS Rare Disease; GMS signed-off
Neuronal ceroid lipofuscinosis type 2 v0.2 Achchuthan Shanmugasundram Panel status changed from internal to public
Neuronal ceroid lipofuscinosis type 2 v0.1 TPP1 Achchuthan Shanmugasundram Deleted their comment
Neuronal ceroid lipofuscinosis type 2 v0.1 TPP1 Achchuthan Shanmugasundram changed review comment from: TPP1 has been added to the panel for R271 Neuronal ceroid lipofuscinosis type 2 with a green rating as agreed with the NHS Genomic Medicine Service.; to: TPP1 has been added to the panel for R271 Neuronal ceroid lipofuscinosis type 2 with a green rating as agreed with the NHS Genomic Medicine Service.
Neuronal ceroid lipofuscinosis type 2 v0.1 TPP1 Achchuthan Shanmugasundram commented on gene: TPP1: TPP1 has been added to the panel for R271 Neuronal ceroid lipofuscinosis type 2 with a green rating as agreed with the NHS Genomic Medicine Service.
Neuronal ceroid lipofuscinosis type 2 v0.1 TPP1 Achchuthan Shanmugasundram reviewed gene: TPP1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Neuronal ceroid lipofuscinosis type 2 v0.1 TPP1 Achchuthan Shanmugasundram gene: TPP1 was added
gene: TPP1 was added to Neuronal ceroid lipofuscinosis type 2. Sources: NHS GMS,Expert Review Green
Mode of inheritance for gene: TPP1 was set to BIALLELIC, autosomal or pseudoautosomal
Neuronal ceroid lipofuscinosis type 2 v0.0 Achchuthan Shanmugasundram Added Panel Neuronal ceroid lipofuscinosis type 2
Set list of related panels to R271
Set panel types to: GMS Rare Disease