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Niemann-Pick disease type A or B v1.2 SMPD1 Achchuthan Shanmugasundram Added comment: Comment on phenotypes: This gene has been associated with relevant phenotypes in OMIM (MIMs #257200 & #607616) and the OMIM records were last accessed on 29 December 2025.
Niemann-Pick disease type A or B v1.2 SMPD1 Achchuthan Shanmugasundram Phenotypes for gene: SMPD1 were changed from to Niemann-Pick disease, type A, OMIM:257200; Niemann-Pick disease, type B, OMIM:607616; Niemann-Pick disease type A, MONDO:0009756; Niemann-Pick disease type B, MONDO:0011871
Niemann-Pick disease type A or B v1.1 Sarah Leigh Panel version 1.0 has been signed off on 2023-09-14
Niemann-Pick disease type A or B v1.0 Sarah Leigh promoted panel to version 1.0
Niemann-Pick disease type A or B v0.3 Sarah Leigh Panel types changed to GMS Rare Disease; GMS signed-off
Niemann-Pick disease type A or B v0.2 Achchuthan Shanmugasundram Panel status changed from internal to public
Niemann-Pick disease type A or B v0.1 SMPD1 Achchuthan Shanmugasundram reviewed gene: SMPD1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: ; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Niemann-Pick disease type A or B v0.1 SMPD1 Achchuthan Shanmugasundram gene: SMPD1 was added
gene: SMPD1 was added to Niemann-Pick disease type A or B. Sources: Expert Review Green,NHS GMS
Mode of inheritance for gene: SMPD1 was set to BIALLELIC, autosomal or pseudoautosomal
Niemann-Pick disease type A or B v0.0 Achchuthan Shanmugasundram Added Panel Niemann-Pick disease type A or B
Set list of related panels to R282
Set panel types to: GMS Rare Disease