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Palmoplantar keratoderma and erythrokeratodermas v1.31 POMP Arina Puzriakova Phenotypes for gene: POMP were changed from Keratosis linearis with ichthyosis congenita and sclerosing keratoderma, 601952 to Keratosis linearis with ichthyosis congenita and sclerosing keratoderma, OMIM:601952
Palmoplantar keratoderma and erythrokeratodermas v1.30 KRT17 Arina Puzriakova Phenotypes for gene: KRT17 were changed from Pachyonychia Congenita, Type 2; Pachyonychia congenita, Jackson-Lawler type, 167210; Steatocystoma multiplex, 184500 to Pachyonychia congenita 2, OMIM:167210; Steatocystoma multiplex, OMIM:184500
Palmoplantar keratoderma and erythrokeratodermas v1.29 SASH1 Arina Puzriakova Phenotypes for gene: SASH1 were changed from Pigmentation defects, palmoplantar keratoderma and skin carcinoma to ?Cancer, alopecia, pigment dyscrasia, onychodystrophy, and keratoderma, OMIM:618373
Palmoplantar keratoderma and erythrokeratodermas v1.28 FAM83G Tom Cullup reviewed gene: FAM83G: Rating: AMBER; Mode of pathogenicity: None; Publications: PMID: 29138053, 31656861, 29963719; Phenotypes: palmoplantar keratoderma, leukonychia, and exuberant curly scalp hair; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Palmoplantar keratoderma and erythrokeratodermas v1.28 KDSR Achchuthan Shanmugasundram Added comment: Comment on publications: Additional case reported in PMID:34686882.
Palmoplantar keratoderma and erythrokeratodermas v1.28 KDSR Achchuthan Shanmugasundram Publications for gene: KDSR were set to 28575652; 34686882
Palmoplantar keratoderma and erythrokeratodermas v1.27 KDSR Achchuthan Shanmugasundram Deleted their comment
Palmoplantar keratoderma and erythrokeratodermas v1.27 KDSR Achchuthan Shanmugasundram Added comment: Comment on publications: Additional patient reported in PMID:34686882.
Palmoplantar keratoderma and erythrokeratodermas v1.27 KDSR Achchuthan Shanmugasundram Publications for gene: KDSR were set to 28575652
Palmoplantar keratoderma and erythrokeratodermas v1.26 JUP Arina Puzriakova Phenotypes for gene: JUP were changed from Naxos disease, 601214; palmoplantar keratoderma (PPK), keratoderma with woolly hair; KERATOSIS PALMOPLANTARIS WITH ARRHYTHMOGENIC CARDIOMYOPATHY; WOOLLY HAIR, PALMOPLANTAR KERATODERMA, AND CARDIAC ABNORMALITIES; PALMOPLANTAR KERATODERMA WITH ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY AND WOOLLY HAIR to Naxos disease, OMIM:601214; Palmoplantar keratoderma, keratoderma with woolly hair, generalised skin fragility, epidermolysis bullosa
Palmoplantar keratoderma and erythrokeratodermas v1.25 DSP Arina Puzriakova Phenotypes for gene: DSP were changed from Striate keratoderma with woolly hair and cardiomyopathy; Keratosis palmoplantaris striata II, 612908; CARVAJAL SYNDROME; Dilated cardiomyopathy with woolly hair and keratoderma, 605676; Arrhythmogenic right ventricular dysplasia 8, 607450; Skin fragility-woolly hair syndrome, 607655; Epidermolysis bullosa, lethal acantholytic; Keratosis palmoplantaris striata II; Skin fragility-woolly hair syndrome; striate keratoderma; diffuse keratoderma; lethal acantholytic epidermolysis bullosa, 609638; alopecia, follicular hyperkeratoses and keratoderma; oligodontia or hypodontia to Cardiomyopathy, dilated, with woolly hair and keratoderma, OMIM:605676 (AR); Dilated cardiomyopathy with woolly hair, keratoderma, and tooth agenesis, OMIM:615821 (AD); Keratosis palmoplantaris striata II, OMIM:612908 (AD)
Palmoplantar keratoderma and erythrokeratodermas v1.24 GJB4 Arina Puzriakova Phenotypes for gene: GJB4 were changed from Erythrokeratodermia variabilis et progressiva 2, 617524 to Erythrokeratodermia variabilis et progressiva 2, OMIM:617524
Palmoplantar keratoderma and erythrokeratodermas v1.23 CARD14 Arina Puzriakova Phenotypes for gene: CARD14 were changed from Pityriasis rubra pilaris, 173200; familial pityriasis rubra pilaris; keratotic follicular papules, well-demarcated salmon-colored erythematous plaques covered with fine powdery scales interspersed with distinct islands of uninvolved skin, and palmoplantar keratoderma to Pityriasis rubra pilaris, OMIM:173200; Psoriasis 2, OMIM:602723; Keratotic follicular papules, well-demarcated salmon-colored erythematous plaques covered with fine powdery scales interspersed with distinct islands of uninvolved skin, and palmoplantar keratoderma
Palmoplantar keratoderma and erythrokeratodermas v1.22 DSC2 Ivone Leong Mode of inheritance for gene: DSC2 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal
Palmoplantar keratoderma and erythrokeratodermas v1.21 DSC2 Ivone Leong Deleted their review
Palmoplantar keratoderma and erythrokeratodermas v1.21 DSC2 Ivone Leong Added comment: Comment on mode of inheritance: MOI changed from "BIALLELIC, autosomal or pseudoautosomal" to "BOTH monoallelic and biallelic, autosomal or pseudoautosomal" as Monoallelic variants in this gene also cause disease.
Palmoplantar keratoderma and erythrokeratodermas v1.21 DSC2 Ivone Leong Mode of inheritance for gene: DSC2 was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Palmoplantar keratoderma and erythrokeratodermas v1.20 GJA1 Arina Puzriakova changed review comment from: Comment on mode of inheritance: MOI was set to 'both mono- and biallelic' in 2017 as PPK has been observed in some patients with oculodentodigital dysplasia (ODDD). Although GJA1-related ODDD can be dominantly (MIM:164200) or recessively (MIM:257850) inherited, of the 4 unrelated families published to date with confirmed recessive ODDD (PMID: 14981729, 16816024, 20597923, 29902798) none have reported dermal abnormalities. It is possible that these may have been overlooked in the context of other more prominent features of the disorder - but this further emphasises the limited value of this panel for this particular phenotype.

MOI for GJA1 on the GMS Palmoplantar keratodermas (R166) panel was set to 'monoallelic' only in 2019, and so the MOI was updated on this panel to reflect this.

Notably, heterozygous variants are also associated with other relevant phenotypes (MIM: 617525 & 104100); to: Comment on mode of inheritance: MOI was set to 'both mono- and biallelic' in 2017 as PPK has been observed in some patients with oculodentodigital dysplasia (ODDD). Although GJA1-related ODDD can be dominantly (MIM:164200) or recessively (MIM:257850) inherited, of the 4 unrelated families published to date with confirmed recessive ODDD (PMID: 14981729, 16816024, 20597923, 29902798) none have reported dermal abnormalities. It is possible that these may have been overlooked in the context of other more prominent features of the disorder - but this further emphasises the limited value of this panel for this particular phenotype.

MOI for GJA1 on the GMS Palmoplantar keratodermas (R166) panel was set to 'monoallelic' in 2019, and so the MOI was also updated to 'monoallelic' on this panel to reflect this.

Notably, heterozygous variants are also associated with other relevant phenotypes (MIM: 617525 & 104100)
Palmoplantar keratoderma and erythrokeratodermas v1.20 GJA1 Arina Puzriakova Mode of inheritance for gene: GJA1 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Palmoplantar keratoderma and erythrokeratodermas v1.19 GJA1 Arina Puzriakova Tag Q3_21_MOI was removed from gene: GJA1.
Tag Q3_21_expert_review was removed from gene: GJA1.
Palmoplantar keratoderma and erythrokeratodermas v1.19 GJA1 Arina Puzriakova changed review comment from: Comment on mode of inheritance: MOI was set to 'both mono- and biallelic' in 2017 as PPK has been observed in some patients with oculodentodigital dysplasia (ODDD). Although GJA1-related ODDD can be dominantly (MIM:164200) or recessively (MIM:257850) inherited, of the 3 unrelated families published to date with confirmed recessive ODDD (PMID: 14981729, 16816024, 29902798) none have reported dermal abnormalities. However, it is possible that these may have been overlooked in the context of other more prominent features of the disorder.

Notably, heterozygous variants are also associated with other relevant phenotypes (MIM: 617525 & 104100)

GJA1 will be flagged for GMS expert review to determine whether the MOI should be changed on this panel (tagged).; to: Comment on mode of inheritance: MOI was set to 'both mono- and biallelic' in 2017 as PPK has been observed in some patients with oculodentodigital dysplasia (ODDD). Although GJA1-related ODDD can be dominantly (MIM:164200) or recessively (MIM:257850) inherited, of the 4 unrelated families published to date with confirmed recessive ODDD (PMID: 14981729, 16816024, 20597923, 29902798) none have reported dermal abnormalities. It is possible that these may have been overlooked in the context of other more prominent features of the disorder - but this further emphasises the limited value of this panel for this particular phenotype.

MOI for GJA1 on the GMS Palmoplantar keratodermas (R166) panel was set to 'monoallelic' only in 2019, and so the MOI was updated on this panel to reflect this.

Notably, heterozygous variants are also associated with other relevant phenotypes (MIM: 617525 & 104100)
Palmoplantar keratoderma and erythrokeratodermas v1.19 GJA1 Arina Puzriakova Tag Q3_21_MOI tag was added to gene: GJA1.
Tag Q3_21_expert_review tag was added to gene: GJA1.
Palmoplantar keratoderma and erythrokeratodermas v1.19 GJA1 Arina Puzriakova Added comment: Comment on mode of inheritance: MOI was set to 'both mono- and biallelic' in 2017 as PPK has been observed in some patients with oculodentodigital dysplasia (ODDD). Although GJA1-related ODDD can be dominantly (MIM:164200) or recessively (MIM:257850) inherited, of the 3 unrelated families published to date with confirmed recessive ODDD (PMID: 14981729, 16816024, 29902798) none have reported dermal abnormalities. However, it is possible that these may have been overlooked in the context of other more prominent features of the disorder.

Notably, heterozygous variants are also associated with other relevant phenotypes (MIM: 617525 & 104100)

GJA1 will be flagged for GMS expert review to determine whether the MOI should be changed on this panel (tagged).
Palmoplantar keratoderma and erythrokeratodermas v1.19 GJA1 Arina Puzriakova Mode of inheritance for gene: GJA1 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Palmoplantar keratoderma and erythrokeratodermas v1.18 GJA1 Arina Puzriakova Phenotypes for gene: GJA1 were changed from Palmoplantar keratoderma with congenital alopecia, 104100; Erythrokeratodermia variabilis et progressiva 3, 617525; Erythrokeratoderma; Palmoplantar keratoderma; Oculodentodigital dysplasia (ODDD) with palmoplantar keratoderma; keratoderma, hypotrichosis and leukonychia to Erythrokeratodermia variabilis et progressiva 3, OMIM:617525; Palmoplantar keratoderma with congenital alopecia, OMIM:104100; Oculodentodigital dysplasia, OMIM:164200
Palmoplantar keratoderma and erythrokeratodermas v1.17 CTSC Catherine Snow Classified gene: CTSC as Green List (high evidence)
Palmoplantar keratoderma and erythrokeratodermas v1.17 CTSC Catherine Snow Added comment: Comment on list classification: Gene added to panel based on feedback from Genomics England clinician.
Palmoplantar keratoderma and erythrokeratodermas v1.17 CTSC Catherine Snow Gene: ctsc has been classified as Green List (High Evidence).
Palmoplantar keratoderma and erythrokeratodermas v1.16 CTSC Zerin Hyder gene: CTSC was added
gene: CTSC was added to Palmoplantar keratoderma and erythrokeratodermas. Sources: Expert list
Mode of inheritance for gene: CTSC was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: CTSC were set to 10581027; 15585850; 11180012; 10662807
Phenotypes for gene: CTSC were set to Papillon-Lefevre syndrome; Haim-Munk syndrome; Periodontitis 1, juvenile
Penetrance for gene: CTSC were set to unknown
Review for gene: CTSC was set to GREEN
gene: CTSC was marked as current diagnostic
Added comment: This gene was part of an initial gene list collated by Thomas Cullup, GOSH and Veronica Kinsler, UCL, 25.Jan.2019 on behalf of the GMS Skin Specialist Test Group.
CTSC green on GMS panel, upgrade on 100K panel.
Sources: Expert list
Palmoplantar keratoderma and erythrokeratodermas KDSR Rebecca Foulger classified KDSR as green
Palmoplantar keratoderma and erythrokeratodermas KDSR Rebecca Foulger added KDSR to panel
Palmoplantar keratoderma and erythrokeratodermas KDSR Rebecca Foulger reviewed KDSR
Palmoplantar keratoderma and erythrokeratodermas ELOVL4 Sarah Leigh added ELOVL4 to panel
Palmoplantar keratoderma and erythrokeratodermas ELOVL4 Sarah Leigh reviewed ELOVL4
Palmoplantar keratoderma and erythrokeratodermas MBTPS2 Rebecca Foulger commented on MBTPS2
Palmoplantar keratoderma and erythrokeratodermas MBTPS2 Rebecca Foulger added MBTPS2 to panel
Palmoplantar keratoderma and erythrokeratodermas MBTPS2 Rebecca Foulger reviewed MBTPS2
Palmoplantar keratoderma and erythrokeratodermas SDR9C7 Rebecca Foulger added SDR9C7 to panel
Palmoplantar keratoderma and erythrokeratodermas SDR9C7 Rebecca Foulger reviewed SDR9C7
Palmoplantar keratoderma and erythrokeratodermas SMARCAD1 Rebecca Foulger classified SMARCAD1 as amber
Palmoplantar keratoderma and erythrokeratodermas SMARCAD1 Rebecca Foulger commented on SMARCAD1
Palmoplantar keratoderma and erythrokeratodermas SMARCAD1 Rebecca Foulger added SMARCAD1 to panel
Palmoplantar keratoderma and erythrokeratodermas SMARCAD1 Rebecca Foulger reviewed SMARCAD1
Palmoplantar keratoderma and erythrokeratodermas Rebecca Foulger promoted panel to version 1
Palmoplantar keratoderma and erythrokeratodermas CAST Sarah Leigh commented on CAST
Palmoplantar keratoderma and erythrokeratodermas POMP Rebecca Foulger classified POMP as red
Palmoplantar keratoderma and erythrokeratodermas MT-TS1 Helen Brittain reviewed MT-TS1
Palmoplantar keratoderma and erythrokeratodermas LIPH Helen Brittain reviewed LIPH
Palmoplantar keratoderma and erythrokeratodermas TAT Helen Brittain reviewed TAT
Palmoplantar keratoderma and erythrokeratodermas POMP Helen Brittain reviewed POMP
Palmoplantar keratoderma and erythrokeratodermas KRT14 Helen Brittain reviewed KRT14
Palmoplantar keratoderma and erythrokeratodermas KRT10 Helen Brittain reviewed KRT10
Palmoplantar keratoderma and erythrokeratodermas KRT1 Helen Brittain reviewed KRT1
Palmoplantar keratoderma and erythrokeratodermas GJB6 Helen Brittain reviewed GJB6
Palmoplantar keratoderma and erythrokeratodermas GJB2 Helen Brittain reviewed GJB2
Palmoplantar keratoderma and erythrokeratodermas DSG1 Helen Brittain reviewed DSG1
Palmoplantar keratoderma and erythrokeratodermas DSC2 Helen Brittain reviewed DSC2
Palmoplantar keratoderma and erythrokeratodermas CARD14 Helen Brittain reviewed CARD14
Palmoplantar keratoderma and erythrokeratodermas ALOXE3 Helen Brittain reviewed ALOXE3
Palmoplantar keratoderma and erythrokeratodermas ALOX12B Helen Brittain reviewed ALOX12B
Palmoplantar keratoderma and erythrokeratodermas DSG2 Ellen Thomas reviewed DSG2
Palmoplantar keratoderma and erythrokeratodermas DES Ellen Thomas reviewed DES
Palmoplantar keratoderma and erythrokeratodermas GJB6 Rebecca Foulger marked GJB6 as ready
Palmoplantar keratoderma and erythrokeratodermas CARD14 Rebecca Foulger marked CARD14 as ready
Palmoplantar keratoderma and erythrokeratodermas POMP Rebecca Foulger commented on POMP
Palmoplantar keratoderma and erythrokeratodermas POMP Rebecca Foulger commented on POMP
Palmoplantar keratoderma and erythrokeratodermas POMP Rebecca Foulger classified POMP as green
Palmoplantar keratoderma and erythrokeratodermas KRT10 Rebecca Foulger classified KRT10 as green
Palmoplantar keratoderma and erythrokeratodermas GJB6 Rebecca Foulger classified GJB6 as green
Palmoplantar keratoderma and erythrokeratodermas LIPH Rebecca Foulger marked LIPH as ready
Palmoplantar keratoderma and erythrokeratodermas LIPH Rebecca Foulger classified LIPH as red
Palmoplantar keratoderma and erythrokeratodermas LIPH Rebecca Foulger commented on LIPH
Palmoplantar keratoderma and erythrokeratodermas CARD14 Rebecca Foulger classified CARD14 as green
Palmoplantar keratoderma and erythrokeratodermas ALOXE3 Rebecca Foulger marked ALOXE3 as ready
Palmoplantar keratoderma and erythrokeratodermas ALOXE3 Rebecca Foulger classified ALOXE3 as green
Palmoplantar keratoderma and erythrokeratodermas ALOX12B Rebecca Foulger marked ALOX12B as ready
Palmoplantar keratoderma and erythrokeratodermas ALOX12B Rebecca Foulger classified ALOX12B as green
Palmoplantar keratoderma and erythrokeratodermas TAT Rebecca Foulger marked TAT as ready
Palmoplantar keratoderma and erythrokeratodermas TAT Rebecca Foulger classified TAT as green
Palmoplantar keratoderma and erythrokeratodermas KRT14 Rebecca Foulger marked KRT14 as ready
Palmoplantar keratoderma and erythrokeratodermas KRT14 Rebecca Foulger classified KRT14 as green
Palmoplantar keratoderma and erythrokeratodermas SLURP1 Rebecca Foulger marked SLURP1 as ready
Palmoplantar keratoderma and erythrokeratodermas KRT1 Rebecca Foulger marked KRT1 as ready
Palmoplantar keratoderma and erythrokeratodermas GJB4 Rebecca Foulger marked GJB4 as ready
Palmoplantar keratoderma and erythrokeratodermas GJB2 Rebecca Foulger marked GJB2 as ready
Palmoplantar keratoderma and erythrokeratodermas DSC2 Rebecca Foulger marked DSC2 as ready
Palmoplantar keratoderma and erythrokeratodermas DSG1 Rebecca Foulger marked DSG1 as ready
Palmoplantar keratoderma and erythrokeratodermas DSC2 Rebecca Foulger classified DSC2 as green
Palmoplantar keratoderma and erythrokeratodermas DSG2 Rebecca Foulger classified DSG2 as red
Palmoplantar keratoderma and erythrokeratodermas DES Rebecca Foulger classified DES as red
Palmoplantar keratoderma and erythrokeratodermas FAM83G Rebecca Foulger marked FAM83G as ready
Palmoplantar keratoderma and erythrokeratodermas KANK2 Rebecca Foulger marked KANK2 as ready
Palmoplantar keratoderma and erythrokeratodermas SASH1 Rebecca Foulger marked SASH1 as ready
Palmoplantar keratoderma and erythrokeratodermas SASH1 Rebecca Foulger classified SASH1 as red
Palmoplantar keratoderma and erythrokeratodermas KRT14 Rebecca Foulger classified KRT14 as amber
Palmoplantar keratoderma and erythrokeratodermas KRT14 Rebecca Foulger commented on KRT14
Palmoplantar keratoderma and erythrokeratodermas KRT10 Rebecca Foulger commented on KRT10
Palmoplantar keratoderma and erythrokeratodermas KANK2 Rebecca Foulger classified KANK2 as red
Palmoplantar keratoderma and erythrokeratodermas GJB6 Rebecca Foulger commented on GJB6
Palmoplantar keratoderma and erythrokeratodermas GJB6 Rebecca Foulger commented on GJB6
Palmoplantar keratoderma and erythrokeratodermas GJB6 Rebecca Foulger commented on GJB6
Palmoplantar keratoderma and erythrokeratodermas FAM83G Rebecca Foulger classified FAM83G as red
Palmoplantar keratoderma and erythrokeratodermas CARD14 Rebecca Foulger commented on CARD14
Palmoplantar keratoderma and erythrokeratodermas ALOXE3 Rebecca Foulger commented on ALOXE3
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger marked GJB3 as ready
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger classified GJB3 as green
Palmoplantar keratoderma and erythrokeratodermas RSPO1 Rebecca Foulger marked RSPO1 as ready
Palmoplantar keratoderma and erythrokeratodermas CAST Rebecca Foulger marked CAST as ready
Palmoplantar keratoderma and erythrokeratodermas CAST Rebecca Foulger classified CAST as green
Palmoplantar keratoderma and erythrokeratodermas CAST Rebecca Foulger commented on CAST
Palmoplantar keratoderma and erythrokeratodermas SLURP1 Rebecca Foulger classified SLURP1 as green
Palmoplantar keratoderma and erythrokeratodermas SERPINB7 Rebecca Foulger marked SERPINB7 as ready
Palmoplantar keratoderma and erythrokeratodermas SERPINB7 Rebecca Foulger classified SERPINB7 as green
Palmoplantar keratoderma and erythrokeratodermas RSPO1 Rebecca Foulger classified RSPO1 as green
Palmoplantar keratoderma and erythrokeratodermas RHBDF2 Rebecca Foulger marked RHBDF2 as ready
Palmoplantar keratoderma and erythrokeratodermas RHBDF2 Rebecca Foulger classified RHBDF2 as green
Palmoplantar keratoderma and erythrokeratodermas JUP Rebecca Foulger marked JUP as ready
Palmoplantar keratoderma and erythrokeratodermas JUP Rebecca Foulger classified JUP as green
Palmoplantar keratoderma and erythrokeratodermas GJB4 Rebecca Foulger classified GJB4 as green
Palmoplantar keratoderma and erythrokeratodermas GJB4 Rebecca Foulger classified GJB4 as green
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger marked GJA1 as ready
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger classified GJA1 as green
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger commented on GJA1
Palmoplantar keratoderma and erythrokeratodermas SLURP1 Edel O'Toole reviewed SLURP1
Palmoplantar keratoderma and erythrokeratodermas CAST Edel O'Toole added CAST to panel
Palmoplantar keratoderma and erythrokeratodermas CAST Edel O'Toole reviewed CAST
Palmoplantar keratoderma and erythrokeratodermas SERPINB7 Edel O'Toole reviewed SERPINB7
Palmoplantar keratoderma and erythrokeratodermas RSPO1 Edel O'Toole reviewed RSPO1
Palmoplantar keratoderma and erythrokeratodermas RHBDF2 Edel O'Toole reviewed RHBDF2
Palmoplantar keratoderma and erythrokeratodermas JUP Edel O'Toole reviewed JUP
Palmoplantar keratoderma and erythrokeratodermas GJB4 Edel O'Toole reviewed GJB4
Palmoplantar keratoderma and erythrokeratodermas GJB3 Edel O'Toole reviewed GJB3
Palmoplantar keratoderma and erythrokeratodermas GJA1 Edel O'Toole reviewed GJA1
Palmoplantar keratoderma and erythrokeratodermas KRT6C Edel O'Toole reviewed KRT6C
Palmoplantar keratoderma and erythrokeratodermas ALOX12B Rebecca Foulger commented on ALOX12B
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Rebecca Foulger marked TRPV3 as ready
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Rebecca Foulger classified TRPV3 as green
Palmoplantar keratoderma and erythrokeratodermas ENPP1 Rebecca Foulger marked ENPP1 as ready
Palmoplantar keratoderma and erythrokeratodermas ENPP1 Rebecca Foulger classified ENPP1 as green
Palmoplantar keratoderma and erythrokeratodermas AQP5 Rebecca Foulger marked AQP5 as ready
Palmoplantar keratoderma and erythrokeratodermas AQP5 Rebecca Foulger classified AQP5 as green
Palmoplantar keratoderma and erythrokeratodermas KANK2 Veronica Kinsler reviewed KANK2
Palmoplantar keratoderma and erythrokeratodermas AQP5 Veronica Kinsler reviewed AQP5
Palmoplantar keratoderma and erythrokeratodermas ENPP1 Veronica Kinsler reviewed ENPP1
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Veronica Kinsler reviewed TRPV3
Palmoplantar keratoderma and erythrokeratodermas AAGAB Veronica Kinsler reviewed AAGAB
Palmoplantar keratoderma and erythrokeratodermas KRT6B Rebecca Foulger marked KRT6B as ready
Palmoplantar keratoderma and erythrokeratodermas RSPO1 Rebecca Foulger classified RSPO1 as amber
Palmoplantar keratoderma and erythrokeratodermas RSPO1 Rebecca Foulger commented on RSPO1
Palmoplantar keratoderma and erythrokeratodermas RSPO1 Rebecca Foulger commented on RSPO1
Palmoplantar keratoderma and erythrokeratodermas RHBDF2 Rebecca Foulger classified RHBDF2 as amber
Palmoplantar keratoderma and erythrokeratodermas TAT Rebecca Foulger classified TAT as amber
Palmoplantar keratoderma and erythrokeratodermas SLURP1 Rebecca Foulger classified SLURP1 as amber
Palmoplantar keratoderma and erythrokeratodermas JUP Rebecca Foulger classified JUP as amber
Palmoplantar keratoderma and erythrokeratodermas CARD14 Rebecca Foulger commented on CARD14
Palmoplantar keratoderma and erythrokeratodermas GJB4 Rebecca Foulger classified GJB4 as amber
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger classified GJB3 as amber
Palmoplantar keratoderma and erythrokeratodermas DSG2 Rebecca Foulger classified DSG2 as green
Palmoplantar keratoderma and erythrokeratodermas DSG2 Rebecca Foulger commented on DSG2
Palmoplantar keratoderma and erythrokeratodermas DES Rebecca Foulger classified DES as green
Palmoplantar keratoderma and erythrokeratodermas DES Rebecca Foulger classified DES as amber
Palmoplantar keratoderma and erythrokeratodermas DES Rebecca Foulger commented on DES
Palmoplantar keratoderma and erythrokeratodermas SERPINB7 Rebecca Foulger classified SERPINB7 as amber
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger classified GJA1 as amber
Palmoplantar keratoderma and erythrokeratodermas ENPP1 Rebecca Foulger classified ENPP1 as amber
Palmoplantar keratoderma and erythrokeratodermas ENPP1 Rebecca Foulger commented on ENPP1
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Rebecca Foulger commented on TRPV3
Palmoplantar keratoderma and erythrokeratodermas AQP5 Rebecca Foulger classified AQP5 as amber
Palmoplantar keratoderma and erythrokeratodermas AQP5 Rebecca Foulger commented on AQP5
Palmoplantar keratoderma and erythrokeratodermas AQP5 Rebecca Foulger commented on AQP5
Palmoplantar keratoderma and erythrokeratodermas DSC2 Rebecca Foulger classified DSC2 as green
Palmoplantar keratoderma and erythrokeratodermas GJB2 Rebecca Foulger commented on GJB2
Palmoplantar keratoderma and erythrokeratodermas SNAP29 Rebecca Foulger marked SNAP29 as ready
Palmoplantar keratoderma and erythrokeratodermas SNAP29 Rebecca Foulger classified SNAP29 as green
Palmoplantar keratoderma and erythrokeratodermas SNAP29 Rebecca Foulger commented on SNAP29
Palmoplantar keratoderma and erythrokeratodermas TAT Rebecca Foulger commented on TAT
Palmoplantar keratoderma and erythrokeratodermas SLURP1 Rebecca Foulger commented on SLURP1
Palmoplantar keratoderma and erythrokeratodermas SERPINB7 Rebecca Foulger commented on SERPINB7
Palmoplantar keratoderma and erythrokeratodermas SERPINB7 Rebecca Foulger commented on SERPINB7
Palmoplantar keratoderma and erythrokeratodermas SERPINB7 Rebecca Foulger commented on SERPINB7
Palmoplantar keratoderma and erythrokeratodermas RSPO1 Rebecca Foulger commented on RSPO1
Palmoplantar keratoderma and erythrokeratodermas RHBDF2 Rebecca Foulger commented on RHBDF2
Palmoplantar keratoderma and erythrokeratodermas RHBDF2 Rebecca Foulger edited their review of RHBDF2
Palmoplantar keratoderma and erythrokeratodermas POMP Rebecca Foulger commented on POMP
Palmoplantar keratoderma and erythrokeratodermas KRT6C Rebecca Foulger classified KRT6C as green
Palmoplantar keratoderma and erythrokeratodermas KRT6C Rebecca Foulger commented on KRT6C
Palmoplantar keratoderma and erythrokeratodermas KRT6C Rebecca Foulger commented on KRT6C
Palmoplantar keratoderma and erythrokeratodermas KRT6C Rebecca Foulger commented on KRT6C
Palmoplantar keratoderma and erythrokeratodermas KRT14 Rebecca Foulger commented on KRT14
Palmoplantar keratoderma and erythrokeratodermas KRT10 Rebecca Foulger commented on KRT10
Palmoplantar keratoderma and erythrokeratodermas KRT10 Rebecca Foulger commented on KRT10
Palmoplantar keratoderma and erythrokeratodermas JUP Rebecca Foulger commented on JUP
Palmoplantar keratoderma and erythrokeratodermas JUP Rebecca Foulger commented on JUP
Palmoplantar keratoderma and erythrokeratodermas GJB6 Rebecca Foulger commented on GJB6
Palmoplantar keratoderma and erythrokeratodermas KRT1 Rebecca Foulger classified KRT1 as green
Palmoplantar keratoderma and erythrokeratodermas KRT1 Rebecca Foulger edited their review of KRT1
Palmoplantar keratoderma and erythrokeratodermas KRT1 Rebecca Foulger commented on KRT1
Palmoplantar keratoderma and erythrokeratodermas KRT6B Rebecca Foulger classified KRT6B as green
Palmoplantar keratoderma and erythrokeratodermas GJB2 Rebecca Foulger commented on GJB2
Palmoplantar keratoderma and erythrokeratodermas GJB2 Rebecca Foulger edited their review of GJB2
Palmoplantar keratoderma and erythrokeratodermas GJB2 Rebecca Foulger classified GJB2 as green
Palmoplantar keratoderma and erythrokeratodermas GJB2 Rebecca Foulger commented on GJB2
Palmoplantar keratoderma and erythrokeratodermas GJB4 Rebecca Foulger edited their review of GJB4
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger commented on GJB3
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger commented on GJB3
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger commented on GJB3
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger commented on GJB3
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger commented on GJA1
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger commented on GJA1
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger commented on GJA1
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger edited their review of GJA1
Palmoplantar keratoderma and erythrokeratodermas ENPP1 Rebecca Foulger commented on ENPP1
Palmoplantar keratoderma and erythrokeratodermas AQP5 Rebecca Foulger commented on AQP5
Palmoplantar keratoderma and erythrokeratodermas ALOXE3 Rebecca Foulger commented on ALOXE3
Palmoplantar keratoderma and erythrokeratodermas ALOX12B Rebecca Foulger commented on ALOX12B
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Rebecca Foulger commented on TRPV3
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Rebecca Foulger commented on TRPV3
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Rebecca Foulger edited their review of TRPV3
Palmoplantar keratoderma and erythrokeratodermas TRPV3 Rebecca Foulger commented on TRPV3
Palmoplantar keratoderma and erythrokeratodermas DSG1 Rebecca Foulger edited their review of DSG1
Palmoplantar keratoderma and erythrokeratodermas DSG1 Rebecca Foulger classified DSG1 as green
Palmoplantar keratoderma and erythrokeratodermas DSC2 Rebecca Foulger edited their review of DSC2
Palmoplantar keratoderma and erythrokeratodermas DSC2 Rebecca Foulger commented on DSC2
Palmoplantar keratoderma and erythrokeratodermas KRT6B Rebecca Foulger commented on KRT6B
Palmoplantar keratoderma and erythrokeratodermas KRT6B Rebecca Foulger edited their review of KRT6B
Palmoplantar keratoderma and erythrokeratodermas KRT6B Rebecca Foulger commented on KRT6B
Palmoplantar keratoderma and erythrokeratodermas KRT6A Rebecca Foulger marked KRT6A as ready
Palmoplantar keratoderma and erythrokeratodermas KRT6A Rebecca Foulger classified KRT6A as green
Palmoplantar keratoderma and erythrokeratodermas KRT6A Rebecca Foulger commented on KRT6A
Palmoplantar keratoderma and erythrokeratodermas AAGAB Rebecca Foulger marked AAGAB as ready
Palmoplantar keratoderma and erythrokeratodermas AAGAB Rebecca Foulger classified AAGAB as green
Palmoplantar keratoderma and erythrokeratodermas AAGAB Rebecca Foulger commented on AAGAB
Palmoplantar keratoderma and erythrokeratodermas SNAP29 Rebecca Foulger commented on SNAP29
Palmoplantar keratoderma and erythrokeratodermas SNAP29 Rebecca Foulger commented on SNAP29
Palmoplantar keratoderma and erythrokeratodermas KRT17 Rebecca Foulger marked KRT17 as ready
Palmoplantar keratoderma and erythrokeratodermas SNAP29 Rebecca Foulger commented on SNAP29
Palmoplantar keratoderma and erythrokeratodermas KRT17 Rebecca Foulger classified KRT17 as green
Palmoplantar keratoderma and erythrokeratodermas KRT17 Rebecca Foulger commented on KRT17
Palmoplantar keratoderma and erythrokeratodermas KRT17 Rebecca Foulger commented on KRT17
Palmoplantar keratoderma and erythrokeratodermas KRT17 Rebecca Foulger edited their review of KRT17
Palmoplantar keratoderma and erythrokeratodermas KRT17 Rebecca Foulger commented on KRT17
Palmoplantar keratoderma and erythrokeratodermas KRT16 Rebecca Foulger marked KRT16 as ready
Palmoplantar keratoderma and erythrokeratodermas KRT16 Rebecca Foulger classified KRT16 as green
Palmoplantar keratoderma and erythrokeratodermas KRT16 Rebecca Foulger commented on KRT16
Palmoplantar keratoderma and erythrokeratodermas KRT9 Rebecca Foulger marked KRT9 as ready
Palmoplantar keratoderma and erythrokeratodermas KRT9 Rebecca Foulger commented on KRT9
Palmoplantar keratoderma and erythrokeratodermas DSP Rebecca Foulger marked DSP as ready
Palmoplantar keratoderma and erythrokeratodermas DSP Rebecca Foulger commented on DSP
Palmoplantar keratoderma and erythrokeratodermas SASH1 Rebecca Foulger commented on SASH1
Palmoplantar keratoderma and erythrokeratodermas RHBDF2 Rebecca Foulger commented on RHBDF2
Palmoplantar keratoderma and erythrokeratodermas MT-TS1 Rebecca Foulger commented on MT-TS1
Palmoplantar keratoderma and erythrokeratodermas KANK2 Rebecca Foulger commented on KANK2
Palmoplantar keratoderma and erythrokeratodermas GJB4 Rebecca Foulger commented on GJB4
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger edited their review of GJB3
Palmoplantar keratoderma and erythrokeratodermas GJB3 Rebecca Foulger commented on GJB3
Palmoplantar keratoderma and erythrokeratodermas GJA1 Rebecca Foulger commented on GJA1
Palmoplantar keratoderma and erythrokeratodermas FAM83G Rebecca Foulger commented on FAM83G
Palmoplantar keratoderma and erythrokeratodermas DSG1 Rebecca Foulger commented on DSG1