ATN1

Panel	Reviews	Mode of inheritance	Details
Filter panels 23 panels
Red ATN1 in Early onset dementia (encompassing fronto-temporal dementia and prion disease) Level 3: Neurodegenerative disorders Level 2: Neurology and neurodevelopmental disorders Version 1.48	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Other Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags currently-ngs-unreportable nucleotide-repeat-expansion
Red ATN1 in Brain channelopathy Level 3: Channelopathies Level 2: Neurology and neurodevelopmental disorders Version 1.55	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Other Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags currently-ngs-unreportable nucleotide-repeat-expansion
Red ATN1 in Ataxia and cerebellar anomalies - narrow panel Version 1.7	review	Other - please specifiy in evaluation comments	Sources Expert Review Red
Red ATN1 in Hereditary ataxia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.202	review	Other - please specifiy in evaluation comments	Sources Expert Review Red Eligibility statement prior genetic testing Tags currently-ngs-unreportable nucleotide-repeat-expansion
Red ATN1 in Dystonia - childhood onset Version 1.8	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags currently-ngs-unreportable nucleotide-repeat-expansion
Red ATN1 in Paroxysmal central nervous system disorders Version 0.168	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red NHS GMS London North GLH Wessex and West Midlands GLH Phenotypes Dentatorubro-pallidoluysian atrophy, 125370
Red ATN1 in Neurodegenerative disorders - adult onset Version 1.106	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Yorkshire and North East GLH NHS GMS South West GLH Expert Review Red Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags currently-ngs-unreportable nucleotide-repeat-expansion
Amber ATN1 in DDG2P Version 1.137	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber DD-Gene2Phenotype Phenotypes congenital hypotonia, epilepsy, developmental delay, digit abnormalities
Green ATN1 in Genetic epilepsy syndromes Level 3: Inherited Epilepsy Syndromes Level 2: Neurology and neurodevelopmental disorders Version 1.365	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Wessex and West Midlands GLH NHS GMS Expert Review Expert Review Green Expert Review Green Expert Review Literature Phenotypes Congenital hypotonia, epilepsy, developmental delay, and digital anomalies, 618494 Global developmental delay Intellectual disability Seizures Generalized hypotonia
Green ATN1 in Intellectual disability Level 3: Neurodevelopmental disorders Level 2: Neurology and neurodevelopmental disorders Version 2.1066	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green BRIDGE study SPEED NEURO Tier1 Gene Phenotypes Generalized hypotonia Global developmental delay Intellectual disability Seizures Feeding difficulties Abnormality of the cardiovascular system Cleft palate Abnormality of the kidney
Red ATN1 in Hereditary ataxia - adult onset Version 1.211	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red NHS GMS Wessex and West Midlands GLH Brain channelopathy v1.46 Hereditary ataxia v1.148 Phenotypes Dentato-pallidoluysian atrophy Dentatorubro-pallidoluysian atrophy 125370 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Red ATN1 in Adult onset movement disorder Version 0.125	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources London North GLH NHS GMS South West GLH Expert Review Red Phenotypes Dentatorubro-pallidoluysian atrophy 125370
Green ATN1_CAG STR in Parkinson Disease and Complex Parkinsonism Level 3: Neurodegenerative disorders Level 2: Neurology and neurodevelopmental disorders Version 1.66	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert Review Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Early onset dementia (encompassing fronto-temporal dementia and prion disease) Level 3: Neurodegenerative disorders Level 2: Neurology and neurodevelopmental disorders Version 1.48	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Brain channelopathy Level 3: Channelopathies Level 2: Neurology and neurodevelopmental disorders Version 1.55	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Ataxia and cerebellar anomalies - narrow panel Version 1.7	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Hereditary ataxia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.202	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Dystonia - childhood onset Version 1.8	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Red ATN1_CAG STR in Paroxysmal central nervous system disorders Version 0.168	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Neurodegenerative disorders - adult onset Version 1.106	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Yorkshire and North East GLH NHS GMS South West GLH London North GLH Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Genetic epilepsy syndromes Level 3: Inherited Epilepsy Syndromes Level 2: Neurology and neurodevelopmental disorders Version 1.365	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Green Expert Review Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Hereditary ataxia - adult onset Version 1.211	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources London North GLH NHS GMS Wessex and West Midlands GLH Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR
Green ATN1_CAG STR in Adult onset movement disorder Version 0.125	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Green Expert list Phenotypes Dentatorubro-pallidoluysian atrophy 125370 Tags STR

ATN1

23 panels

Red ATN1 in Early onset dementia (encompassing fronto-temporal dementia and prion disease)

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Phenotypes

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Red ATN1 in Brain channelopathy

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Phenotypes

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Red ATN1 in Ataxia and cerebellar anomalies - narrow panel

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Red ATN1 in Hereditary ataxia

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Red ATN1 in Dystonia - childhood onset

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Phenotypes

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Red ATN1 in Paroxysmal central nervous system disorders

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Phenotypes

Red ATN1 in Neurodegenerative disorders - adult onset

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Phenotypes

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Amber ATN1 in DDG2P

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Phenotypes

Green ATN1 in Genetic epilepsy syndromes

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Phenotypes

Green ATN1 in Intellectual disability

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Phenotypes

Red ATN1 in Hereditary ataxia - adult onset

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Phenotypes

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Red ATN1 in Adult onset movement disorder

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Phenotypes

Green ATN1_CAG STR in Parkinson Disease and Complex Parkinsonism

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Green ATN1_CAG STR in Early onset dementia (encompassing fronto-temporal dementia and prion disease)

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Phenotypes

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Green ATN1_CAG STR in Brain channelopathy

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Phenotypes

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Green ATN1_CAG STR in Ataxia and cerebellar anomalies - narrow panel

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Phenotypes

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Green ATN1_CAG STR in Hereditary ataxia

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Phenotypes

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Green ATN1_CAG STR in Dystonia - childhood onset

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Phenotypes

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Red ATN1_CAG STR in Paroxysmal central nervous system disorders

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Phenotypes

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Green ATN1_CAG STR in Neurodegenerative disorders - adult onset

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Phenotypes

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Green ATN1_CAG STR in Genetic epilepsy syndromes

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Phenotypes

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Green ATN1_CAG STR in Hereditary ataxia - adult onset

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