CD59

CD59 molecule (CD59 blood group)
OMIM: 107271, Gene2Phenotype

7 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 7 panels
Green CD59 in COVID-19 research Level 2: Viral research Version 1.141	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes Primary CD59 deficiency paroxysmal nocturnal haemoglobinuria CD59 antigen P18-20 deficiency (CD59) Hemolytic anemia, polyneuropathy Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy, 612300 childhood relapsing immune-mediated polyneuropathy Complement Deficiencies chronic hemolysis Membrane Attack Complex Inhibitor (CD59) deficiency
Green CD59 in Primary immunodeficiency or monogenic inflammatory bowel disease Version 4.201 Latest signed off version: v4.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services Expert Review Green ESID Registry 20171117 GRID V2.0 Phenotypes Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy, 612300 CD59 antigen P18-20 deficiency (CD59) Membrane Attack Complex Inhibitor (CD59) deficiency Primary CD59 deficiency paroxysmal nocturnal haemoglobinuria chronic hemolysis childhood relapsing immune-mediated polyneuropathy Hemolytic anemia, polyneuropathy Complement Deficiencies
Green CD59 in Cytopenias and congenital anaemias Level 3: Anaemias and red cell disorders Level 2: Haematological disorders Version 1.118	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Radboud University Medical Center, Nijmegen Phenotypes Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy, 612300
Green CD59 in Rare anaemia Version 3.8 Latest signed off version: v3.0 (22 Mar 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green North West GLH NHS GMS Yorkshire and North East GLH Phenotypes 305000 Dyskeratosis congenita, X-linked Dyskeratosis congenita, X-linked, 305000
Green CD59 in Hereditary neuropathy Level 3: Motor and Sensory Disorders of the PNS Level 2: Neurology and neurodevelopmental disorders Version 1.477	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS London North GLH Phenotypes Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy, 612300 Onset 1st and 2nd decade. Haemolytic anaemia, strokes and relapsing immune-mediated demyelinating neuropathy
Amber CD59 in Hereditary neuropathy or pain disorder Version 3.94 Latest signed off version: v3.24 (15 May 2023)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber London North GLH NHS GMS NHS GMS London North GLH Phenotypes Onset 1st and 2nd decade. Haemolytic anaemia, strokes and relapsing immune-mediated demyelinating neuropathy Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy, 612300
Green CD59 in Severe Paediatric Disorders Version 1.184	review	BIALLELIC, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy, 612300