DDX41

DEAD-box helicase 41
OMIM: 608170, Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Green DDX41 in Haematological malignancies for rare disease Level 3: Tumour syndromes Level 2: Tumour syndromes Version 1.17	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Curated sources Phenotypes Class: familial predisp to leukaemia (typ AD) DDX41-related AML SCN3 AML, MDS (late onset), possibly others CML No other known cancer risks
Green DDX41 in Inherited predisposition to acute myeloid leukaemia (AML) Version 3.3 Latest signed off version: v3.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green North West GLH Yorkshire and North East GLH NHS GMS Wessex and West Midlands GLH Phenotypes {Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to}, OMIM:616871 DDX41-related hematologic malignancy predisposition syndrome, MONDO:0014809
Green DDX41 in Haematological malignancies cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 4.4 Latest signed off version: v4.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green Curated sources Phenotypes Class: familial predisp to leukaemia (typ AD) DDX41-related AML SCN3 AML, MDS (late onset), possibly others CML No other known cancer risks
Green DDX41 in Cytopenia - NOT Fanconi anaemia Version 3.33 Latest signed off version: v3.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green NHS GMS London South GLH Phenotypes Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to, 616871