1. Genes and Genomic Entities
  2. DGKE

DGKE

diacylglycerol kinase epsilon
OMIM: 601440, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green DGKE in Membranoproliferative glomerulonephritis including C3 glomerulopathy


Level 2: Renal
Version 3.8
Latest signed off version: v3.6 (30 Apr 2025)

Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • Expert list
    Phenotypes
    • Haemolytic uraemic syndrome
    • aHUS
    • Hemolytic uremic syndrome, atypical, susceptibility to, 7, 615008
    • Nephrotic syndrome, type 7, 615008
    • C3 glomerulopathy
    • C3G
    • Immune complex MPGN
    • IC-MPGN
    Green DGKE in Atypical haemolytic uraemic syndrome


    Level 2: Renal
    Version 3.8
    Latest signed off version: v3.6 (30 Apr 2025)

    Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • UKGTN
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Hemolytic uremic syndrome, atypical, susceptibility to, 7 615008
    Green DGKE in Unexplained kidney failure in young people

    Level 3: Disorders of function
    Level 2: Renal and urinary tract disorders
    Version 1.124

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Emory Genetics Laboratory
    • Expert list
    • Radboud University Medical Center, Nijmegen
    • Expert Review
    • UKGTN
    Phenotypes
    • Nephrotic syndrome, type 7 615008
    • {Hemolytic uremic syndrome, atypical, susceptibility to, 7} 615008
    Green DGKE in Proteinuric renal disease


    Level 2: Renal
    Version 5.7
    Latest signed off version: v5.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • NHS GMS
    Phenotypes
    • Nephrotic syndrome, type 7, OMIM:615008