DGKE

diacylglycerol kinase epsilon
OMIM: 601440, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels

Green DGKE in Membranoproliferative glomerulonephritis

Level 3: Syndromes with prominent renal abnormalities
Level 2: Renal and urinary tract disorders
Version 2.21
Latest signed off version: v2.13 (16 Oct 2020)

Component of the following Super Panels:

  • Renal superpanel - broad
  • Renal superpanel - narrow
  • review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • Expert list
    Phenotypes
    • Haemolytic uraemic syndrome
    • aHUS
    • Hemolytic uremic syndrome, atypical, susceptibility to, 7, 615008
    • Nephrotic syndrome, type 7, 615008
    • C3 glomerulopathy
    • C3G
    • Immune complex MPGN
    • IC-MPGN
    Tags
    • for-review

    Green DGKE in Atypical haemolytic uraemic syndrome

    Level 3: Syndromes with prominent renal abnormalities
    Level 2: Renal and urinary tract disorders
    Version 2.10
    Latest signed off version: v2.2 (13 Feb 2020)

    Component of the following Super Panels:

  • Renal superpanel - broad
  • Renal superpanel - narrow
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • UKGTN
    • Radboud University Medical Center, Nijmegen
    Phenotypes
    • Hemolytic uremic syndrome, atypical, susceptibility to, 7 615008

    Green DGKE in Unexplained kidney failure in young people

    Level 3: Disorders of function
    Level 2: Renal and urinary tract disorders
    Version 1.99

    Component of the following Super Panels:

  • Renal superpanel - broad
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Emory Genetics Laboratory
    • Expert Review
    • Radboud University Medical Center, Nijmegen
    • Expert list
    • UKGTN
    Phenotypes
    • Nephrotic syndrome, type 7 615008
    • {Hemolytic uremic syndrome, atypical, susceptibility to, 7} 615008

    Green DGKE in Unexplained paediatric onset end-stage renal disease


    Version 1.23
    Latest signed off version: v1.2 (4 Mar 2020)

    Component of the following Super Panels:

  • Renal superpanel - broad
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    Phenotypes
    • Nephrotic syndrome, type 7 615008
    • {Hemolytic uremic syndrome, atypical, susceptibility to, 7} 615008

    Amber DGKE in Proteinuric renal disease

    Level 3: Syndromes with prominent renal abnormalities
    Level 2: Renal and urinary tract disorders
    Version 2.61
    Latest signed off version: v2.32 (16 Oct 2020)

    Component of the following Super Panels:

  • Renal superpanel - broad
  • Renal superpanel - narrow
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • NHS GMS
    Phenotypes
    • Nephrotic syndrome, type 7 #615008
    Tags
    • for-review

    Green DGKE in Severe Paediatric Disorders


    Version 1.84

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Next Generation Children Project
    • Expert Review Green
    • Expert list
    Phenotypes
    • Nephrotic syndrome, type 7, 615008