1. Genes and Genomic Entities
  2. DOCK3

DOCK3

dedicator of cytokinesis 3
OMIM: 603123, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels
Green DOCK3 in Ataxia and cerebellar anomalies - narrow panel


Level 2: Neurology
Version 8.63
Latest signed off version: v8.0 (30 Apr 2025)

Component of the following Super Panels:

  • Hereditary ataxia and cerebellar anomalies - childhood onset

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS GMS
    • Expert Review Green
    • Expert list
    Phenotypes
    • Neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia OMIM:618292
    • neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia MONDO:0032661
    Green DOCK3 in DDG2P


    Version 6.424
    Latest signed off version: v6.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • DOCK3-related neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia
    • MONDO:0032661
    • OMIM:618292.0
    Green DOCK3 in Intellectual disability


    Level 2: Developmental disorders
    Version 9.285
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    • Literature
    Phenotypes
    • Neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia OMIM:618292
    • neurodevelopmental disorder with impaired intellectual development, hypotonia, and ataxia MONDO:0032661