FGA

fibrinogen alpha chain
OMIM: 134820, Gene2Phenotype

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Green FGA in Periodic fever syndromes Level 3: Multi-system inflammatory/autoimmune disorders Level 2: Rheumatological disorders Version 1.34	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Eligibility statement prior genetic testing Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Phenotypes Amyloidosis, familial visceral, OMIM:105200
Green FGA in Hereditary systemic amyloidosis Level 2: Renal Version 1.28 Latest signed off version: v1.24 (30 Apr 2025) Component of the following Super Panels: Unexplained young onset end-stage renal disease	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Green Phenotypes Amyloidosis, familial visceral, OMIM:105200
Green FGA in Inherited bleeding disorders Level 3: Haemostasis disorders Level 2: Haematological and immunological disorders Version 1.182	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Radboud University Medical Center, Nijmegen Other Expert Review Green BRIDGE Study Tier 1 Gene Phenotypes Fibrinogen deficiency Hypodysfibrinogenemia,congenital,616004 Dysfibrinogenemia,congenital,616004 thrombosis Fibrinogen Dusart dysfibrinogenemia associated with recurrent thrombosis thrombophilia prolonged thrombin clotting Fibrinogen Caracas II
Green FGA in Thrombophilia with a likely monogenic cause Level 2: Haematology Version 2.10 Latest signed off version: v2.2 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources North West GLH Yorkshire and North East GLH London South GLH NHS GMS Expert Review Green Wessex and West Midlands GLH Phenotypes 202400 Afibrinogenemia, congenital 105200 Amyloidosis, familial visceral 616004 Dysfibrinogenemia, congenital 616004 Hypodysfibrinogenemia, congenital
Green FGA in Bleeding and platelet disorders Level 2: Haematology Version 4.6 Latest signed off version: v4.0 (30 Apr 2025)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources North West GLH Yorkshire and North East GLH London South GLH NHS GMS Expert Review Green Wessex and West Midlands GLH Phenotypes 202400 Afibrinogenemia, congenital 616004 Hypodysfibrinogenemia, congenital 105200 Amyloidosis, familial visceral 616004 Dysfibrinogenemia, congenital