FGA

fibrinogen alpha chain
OMIM: 134820, Gene2Phenotype

7 panels

Panel Reviews Mode of inheritance Details
7 panels

Green FGA in Periodic fever syndromes

Level 3: Multi-system inflammatory/autoimmune disorders
Level 2: Rheumatological disorders
Version 1.15

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Eligibility statement prior genetic testing
  • Illumina TruGenome Clinical Sequencing Services
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Amyloidosis, familial visceral 105200

Green FGA in Amyloidosis


Version 1.11
Latest signed off version: v1.2 (13 Feb 2020)

Component of the following Super Panels:

  • Renal superpanel - broad
  • review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • NHS GMS
    • Expert Review Green
    Phenotypes
    • Amyloidosis, familial visceral 105200

    Green FGA in Inherited bleeding disorders

    Level 3: Haemostasis disorders
    Level 2: Haematological and immunological disorders
    Version 1.164

    review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Other
    • Radboud University Medical Center, Nijmegen
    • Expert Review Green
    • BRIDGE Study Tier 1 Gene
    Phenotypes
    • Fibrinogen deficiency
    • Hypodysfibrinogenemia,congenital,616004
    • Dysfibrinogenemia,congenital,616004
    • thrombosis
    • Fibrinogen Dusart
    • dysfibrinogenemia associated with recurrent thrombosis
    • thrombophilia
    • prolonged thrombin clotting
    • Fibrinogen Caracas II

    Red FGA in Autism


    Version 0.22

    review Not set
    Sources
    • Expert Review Red
    • SFARI

    Green FGA in Thrombophilia


    Version 1.20
    Latest signed off version: v1.2 (3 Mar 2020)

    review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • North West GLH
    • Yorkshire and North East GLH
    • London South GLH
    • NHS GMS
    • Expert Review Green
    • Wessex and West Midlands GLH
    Phenotypes
    • 202400 Afibrinogenemia, congenital
    • 105200 Amyloidosis, familial visceral
    • 616004 Dysfibrinogenemia, congenital
    • 616004 Hypodysfibrinogenemia, congenital

    Green FGA in Bleeding and platelet disorders


    Version 1.31
    Latest signed off version: v1.2 (3 Mar 2020)

    review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • North West GLH
    • Yorkshire and North East GLH
    • London South GLH
    • NHS GMS
    • Expert Review Green
    • Wessex and West Midlands GLH
    Phenotypes
    • 202400 Afibrinogenemia, congenital
    • 616004 Hypodysfibrinogenemia, congenital
    • 105200 Amyloidosis, familial visceral
    • 616004 Dysfibrinogenemia, congenital

    Green FGA in Severe Paediatric Disorders


    Version 1.84

    review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Next Generation Children Project
    • Expert Review Green
    • Expert list
    Phenotypes
    • Dysfibrinogenemia, congenital, 616004
    • Hypodysfibrinogenemia, congenital, 616004
    • Amyloidosis, familial visceral, 105200
    • Afibrinogenemia, congenital, 202400