FGA

fibrinogen alpha chain
OMIM: 134820, Gene2Phenotype

8 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 8 panels
Green FGA in Periodic fever syndromes Level 3: Multi-system inflammatory/autoimmune disorders Level 2: Rheumatological disorders Version 1.33	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Eligibility statement prior genetic testing Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Phenotypes Amyloidosis, familial visceral, OMIM:105200
Green FGA in Hereditary systemic amyloidosis Version 1.21 Latest signed off version: v1.18 (22 Mar 2023) Component of the following Super Panels: Renal superpanel - broad	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Green Phenotypes Amyloidosis, familial visceral, OMIM:105200
Green FGA in Inherited bleeding disorders Level 3: Haemostasis disorders Level 2: Haematological and immunological disorders Version 1.177	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Other Radboud University Medical Center, Nijmegen Expert Review Green BRIDGE Study Tier 1 Gene Phenotypes Fibrinogen deficiency Hypodysfibrinogenemia,congenital,616004 Dysfibrinogenemia,congenital,616004 thrombosis Fibrinogen Dusart dysfibrinogenemia associated with recurrent thrombosis thrombophilia prolonged thrombin clotting Fibrinogen Caracas II
Red FGA in Autism Version 0.36	review	Not set	Sources Expert Review Red SFARI
Green FGA in Thrombophilia with a likely monogenic cause Version 2.5 Latest signed off version: v2.2 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources North West GLH Yorkshire and North East GLH London South GLH NHS GMS Expert Review Green Wessex and West Midlands GLH Phenotypes 202400 Afibrinogenemia, congenital 105200 Amyloidosis, familial visceral 616004 Dysfibrinogenemia, congenital 616004 Hypodysfibrinogenemia, congenital
Green FGA in Bleeding and platelet disorders Version 3.9 Latest signed off version: v3.0 (22 Mar 2023)	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources North West GLH Yorkshire and North East GLH London South GLH NHS GMS Expert Review Green Wessex and West Midlands GLH Phenotypes 202400 Afibrinogenemia, congenital 616004 Hypodysfibrinogenemia, congenital 105200 Amyloidosis, familial visceral 616004 Dysfibrinogenemia, congenital
Amber FGA in Unexplained young onset end-stage renal disease Version 3.40 Latest signed off version: v3.0 (22 Mar 2023) Component of the following Super Panels: Renal superpanel - broad	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Amber Phenotypes Amyloidosis, familial visceral, OMIM:105200 Tags Q4_23_promote_green
Green FGA in Severe Paediatric Disorders Version 1.184	review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Dysfibrinogenemia, congenital, 616004 Hypodysfibrinogenemia, congenital, 616004 Amyloidosis, familial visceral, 105200 Afibrinogenemia, congenital, 202400