Inherited bleeding disorders

Gene: FGA

Green List (high evidence)

FGA (fibrinogen alpha chain)
EnsemblGeneIds (GRCh38): ENSG00000171560
EnsemblGeneIds (GRCh37): ENSG00000171560
OMIM: 134820, Gene2Phenotype
FGA is in 6 panels

2 reviews

Louise Daugherty (Genomics England Curator)

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Phenotypes
Fibrinogen deficiency

BRIDGE consortium (NIHRBR-RD)

Green List (high evidence)

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Phenotypes
Fibrinogen deficiency

Variants in this GENE are reported as part of current diagnostic practice

Details

Mode of Inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Other
  • Radboud University Medical Center, Nijmegen
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Fibrinogen deficiency
  • Hypodysfibrinogenemia,congenital,616004
  • Dysfibrinogenemia,congenital,616004
  • thrombosis
  • Fibrinogen Dusart
  • dysfibrinogenemia associated with recurrent thrombosis
  • thrombophilia
  • prolonged thrombin clotting
  • Fibrinogen Caracas II
OMIM
134820
Clinvar variants
Variants in FGA
Penetrance
Complete
Panels with this gene

History Filter Activity

19 Dec 2016, Gel status: 4

panel promoted to version 1

Louise Daugherty (Genomics England Curator)

Revised 19 December 2016

19 Dec 2016, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

FGA was added to Inherited bleeding disorderspanel. Source: Radboud University Medical Center, Nijmegen FGA was added to Inherited bleeding disorderspanel. Source: Other

19 Dec 2016, Gel status: 4

Added New Source

Louise Daugherty (Genomics England Curator)

FGA was added to Inherited bleeding disorderspanel. Source: Expert Review Green

9 Sep 2016, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

FGA was added to Inherited bleeding disorderspanel. Sources: BRIDGE Study Tier 1 Gene

9 Sep 2016, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

FGA was created by ellenmcdonagh