Inherited bleeding disorders
Gene: VWF
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
von Willebrand factor type 1; von Willebrand factor type 2A; von Willebrand factor type 2B; von Willebrand factor type 2M; von Willebrand factor type 2N; von Willebrand factor type 3
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
von Willebrand factor type 1; von Willebrand factor type 2A; von Willebrand factor type 2B; von Willebrand factor type 2M; von Willebrand factor type 2N; von Willebrand factor type 3
Variants in this GENE are reported as part of current diagnostic practice
Mode of inheritance for VWF was changed to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Revised 19 December 2016
VWF was added to Inherited bleeding disorderspanel. Source: Expert Review Green Model of inheritance for gene VWF was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
VWF was added to Inherited bleeding disorderspanel. Sources: BRIDGE Study Tier 1 Gene
VWF was created by ellenmcdonagh