Inherited bleeding disorders
Gene: FGB
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Fibrinogen deficiency
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Fibrinogen deficiency
Variants in this GENE are reported as part of current diagnostic practice
Revised 19 December 2016
Mode of inheritance for FGB was changed to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
FGB was added to Inherited bleeding disorderspanel. Source: Radboud University Medical Center, Nijmegen FGB was added to Inherited bleeding disorderspanel. Source: Other Model of inheritance for gene FGB was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
FGB was added to Inherited bleeding disorderspanel. Source: Expert Review Green Model of inheritance for gene FGB was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
FGB was created by ellenmcdonagh
FGB was added to Inherited bleeding disorderspanel. Sources: BRIDGE Study Tier 1 Gene