Inherited bleeding disorders
Gene: PROC
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Protein C deficiency
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Protein C deficiency
Variants in this GENE are reported as part of current diagnostic practice
Eligibility statement prior genetic testing was added to PROC. Panel: Inherited bleeding disorders
Revised 19 December 2016
PROC was added to Inherited bleeding disorderspanel. Source: Illumina TruGenome Clinical Sequencing Services PROC was added to Inherited bleeding disorderspanel. Source: Radboud University Medical Center, Nijmegen PROC was added to Inherited bleeding disorderspanel. Source: UKGTN Model of inheritance for gene PROC was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
PROC was added to Inherited bleeding disorderspanel. Source: Expert Review Green Model of inheritance for gene PROC was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
PROC was created by ellenmcdonagh
PROC was added to Inherited bleeding disorderspanel. Sources: BRIDGE Study Tier 1 Gene