FOXC2

forkhead box C2
OMIM: 602402, Gene2Phenotype

14 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 14 panels
Green FOXC2 in Fetal hydrops Level 3: Fetal disorders Level 2: Dysmorphic and congenital abnormality syndromes Version 1.28	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Other Literature Phenotypes Lymphedema-distichiasis syndrome, 153400 fetal hydrops
Red FOXC2 in Diabetes with additional phenotypes suggestive of a monogenic aetiology Level 3: Disorders of unusual phenotypes Level 2: Endocrine disorders Version 1.60	review	Not set	Sources Expert Review Red Radboud University Medical Center, Nijmegen Phenotypes Lymphedema-distichiasis syndrome, 153400 Lymphedema-distichiasis syndrome with renal disease and diabetes mellitus, 153400
Amber FOXC2 in Rare genetic inflammatory skin disorders Version 1.38 Signed off v.1.6 on 15 Oct 2020	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Amber
Red FOXC2 in Unexplained kidney failure in young people Level 3: Disorders of function Level 2: Renal and urinary tract disorders Version 1.92 Component of the following Super Panels: Renal superpanel - broad	review	Not set	Sources Expert Review Red Expert list
Green FOXC2 in Vascular skin disorders Version 1.47 Signed off v.1.3 on 15 Oct 2020	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources London North GLH NHS GMS Expert Review Green Phenotypes Lymphoedema-distichiasis syndrome, OMIM:153400
No list FOXC2 in Monogenic diabetes Version 2.41 Signed off v.2.2 on 25 Feb 2020	review	Unknown	Sources Expert Review Removed Phenotypes Lymphedema-distichiasis syndrome with renal disease and diabetes mellitus, 153400 Lymphedema-distichiasis syndrome, 153400 Tags curated_removed
Red FOXC2 in CAKUT Level 3: Structural renal and urinary tract disease Level 2: Renal and urinary tract disorders Version 1.160 Component of the following Super Panels: Renal superpanel - broad Renal superpanel - narrow	review	Not set	Sources Expert Review Red Expert list
Red FOXC2 in Unexplained paediatric onset end-stage renal disease Version 1.16 Signed off v.1.2 on 4 Mar 2020 Component of the following Super Panels: Renal superpanel - broad	review	Unknown	Sources Expert Review Red
Green FOXC2 in Fetal anomalies Version 1.641 Signed off v.1.92 on 21 Aug 2020	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources PAGE DD-Gene2Phenotype Expert Review Green Phenotypes LYMPHEDEMA-DISTICHIASIS SYNDROME HEREDITARY LYMPHEDEMA II
Green FOXC2 in DDG2P Version 2.25 Signed off v.2.2 on 13 Feb 2020 Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources DD-Gene2Phenotype Expert Review Green Phenotypes LYMPHEDEMA-DISTICHIASIS SYNDROME 153400 HEREDITARY LYMPHEDEMA II 241432
Green FOXC2 in Clefting Level 3: Dysmorphic disorders Level 2: Dysmorphic and congenital abnormality syndromes Version 2.24 Signed off v.2.2 on 4 Mar 2020 Component of the following Super Panels: Paediatric disorders	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Victorian Clinical Genetics Services Expert Review Green Phenotypes LYMPHEDEMA-DISTICHIASIS SYNDROME Cleft palate
Red FOXC2 in Intellectual disability Level 3: Neurodevelopmental disorders Level 2: Neurology and neurodevelopmental disorders Version 3.1018 Signed off v.3.2 on 13 Feb 2020 Component of the following Super Panels: Hypotonic infant Paediatric disorders White matter disorders - childhood onset	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Red BRIDGE study SPEED NEURO Tier1 Gene Phenotypes Lymphedema-distichiasis syndrome, 153400 Lymphedema-distichiasis syndrome with renal disease and diabetes mellitus, 153400
Green FOXC2 in Primary lymphoedema Level 3: Lymphatic Disorders Level 2: Cardiovascular disorders Version 2.8 Signed off v.2.2 on 2 Mar 2020	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources London South GLH Eligibility statement prior genetic testing Radboud University Medical Center, Nijmegen UKGTN Expert Review Green Phenotypes Lymphedema-distichiasis syndrome, 153400 Lymphedema-distichiasis syndrome with renal disease and diabetes mellitus, 153400
Green FOXC2 in Severe Paediatric Disorders Version 1.75	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Lymphedema-distichiasis syndrome with renal disease and diabetes mellitus, 153400 Lymphedema-distichiasis syndrome, 153400