HEATR5B

HEAT repeat containing 5B
Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Amber HEATR5B in Ataxia and cerebellar anomalies - narrow panel


Level 2: Neurology
Version 8.63
Latest signed off version: v8.0 (30 Apr 2025)

Component of the following Super Panels:

  • Hereditary ataxia and cerebellar anomalies - childhood onset
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • Literature
    Phenotypes
    • pontocerebellar hypoplasia, MONDO:0020135
    • intellectual disability, MONDO:0001071
    • seizures
    Tags
    • Q3_25_promote_green
    • Q3_25_expert_review
    Green HEATR5B in Cerebellar hypoplasia

    Level 3: Motor Disorders of the CNS
    Level 2: Neurology and neurodevelopmental disorders
    Version 1.86

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • pontocerebellar hypoplasia, MONDO:0020135
    • intellectual disability, MONDO:0001071
    • seizures
    Red HEATR5B in DDG2P


    Version 6.424
    Latest signed off version: v6.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • DD-Gene2Phenotype
    • Expert Review Red
    Phenotypes
    • HEATR5B-related pontocerebellar hypoplasia
    Amber HEATR5B in Early onset or syndromic epilepsy


    Level 2: Neurology
    Version 8.125
    Latest signed off version: v8.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders
  • Unexplained death in infancy and sudden unexplained death in childhood
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Literature
    • Expert Review Amber
    Phenotypes
    • pontocerebellar hypoplasia, MONDO:0020135
    • intellectual disability, MONDO:0001071
    • seizures
    Tags
    • watchlist
    Amber HEATR5B in Intellectual disability


    Level 2: Developmental disorders
    Version 9.285
    Latest signed off version: v9.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Childhood onset leukodystrophy
  • Hypotonic infant
  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • Literature
    Phenotypes
    • pontocerebellar hypoplasia, MONDO:0020135
    • intellectual disability, MONDO:0001071
    • seizures
    Tags
    • watchlist