HTT

23 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 23 panels
Red HTT in Parkinson Disease and Complex Parkinsonism Level 3: Neurodegenerative disorders Level 2: Neurology and neurodevelopmental disorders Version 1.128	review	Other	Sources Expert Review Red Expert Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Red HTT in Brain channelopathy Level 3: Channelopathies Level 2: Neurology and neurodevelopmental disorders Version 1.83	review	Other	Sources Expert Review Red Expert Review Phenotypes Huntington disease, OMIM:143100 Tags currently-ngs-unreportable nucleotide-repeat-expansion
Red HTT in Structural basal ganglia disorders Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.40	review	Other	Sources Expert Review Red Literature Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Red HTT in Paroxysmal central nervous system disorders Level 2: Neurology Version 4.2 Latest signed off version: v4.0 (30 Apr 2025)	review	Other	Sources Expert Review Red NHS GMS London North GLH Wessex and West Midlands GLH Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Red HTT in Adult onset neurodegenerative disorder Level 2: Neurology Version 8.11 Latest signed off version: v8.0 (30 Apr 2025)	review	Other	Sources NHS GMS Yorkshire and North East GLH Expert Review Red Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Red HTT in Possible mitochondrial disorder - nuclear genes Level 2: Mitochondrial Version 4.20 Latest signed off version: v4.0 (30 Apr 2025)	review	Other	Sources NHS GMS Expert Review Red Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Amber HTT in Intellectual disability Level 2: Developmental disorders Version 9.285 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber BRIDGE study SPEED NEURO Tier1 Gene Phenotypes Lopes-Maciel-Rodan syndrome, OMIM:617435 LOMARS Tags watchlist
Red HTT in Mitochondrial disorders Level 2: Mitochondrial Version 9.41 Latest signed off version: v9.0 (30 Apr 2025) Component of the following Super Panels: Childhood onset leukodystrophy	review	Other	Sources Expert Review Red NHS GMS Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Red HTT in Hereditary ataxia with onset in adulthood Level 2: Neurology Version 8.23 Latest signed off version: v8.0 (30 Apr 2025)	review	Other	Sources Expert Review Red London North GLH NHS GMS Wessex and West Midlands GLH Brain channelopathy v1.46 Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Red HTT in Adult onset dystonia, chorea or related movement disorder Level 2: Neurology Version 5.3 Latest signed off version: v5.0 (30 Apr 2025)	review	Other	Sources NHS GMS South West GLH Expert Review Red Phenotypes Huntington disease, OMIM:143100 Tags nucleotide-repeat-expansion currently-ngs-unreportable
Amber HTT in Childhood onset dystonia, chorea or related movement disorder Level 2: Neurology Version 7.13 Latest signed off version: v7.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber South West GLH Phenotypes Lopes-Maciel-Rodan syndrome, OMIM:617435 LOMARS Tags watchlist
Green HTT_CAG STR in Parkinson Disease and Complex Parkinsonism Level 3: Neurodegenerative disorders Level 2: Neurology and neurodevelopmental disorders Version 1.128	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green NHS GMS Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR
Green HTT_CAG STR in Early onset dementia (encompassing fronto-temporal dementia and prion disease) Level 3: Neurodegenerative disorders Level 2: Neurology and neurodevelopmental disorders Version 1.84	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green NHS GMS Expert Review Phenotypes Huntington disease, OMIM:143100 Tags STR
No list HTT_CAG STR in Brain channelopathy Level 3: Channelopathies Level 2: Neurology and neurodevelopmental disorders Version 1.83	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Removed Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR curated_removed
No list HTT_CAG STR in Ataxia and cerebellar anomalies - narrow panel Level 2: Neurology Version 8.63 Latest signed off version: v8.0 (30 Apr 2025) Component of the following Super Panels: Hereditary ataxia and cerebellar anomalies - childhood onset	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Removed Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR curated_removed
Green HTT_CAG STR in Hereditary ataxia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.344	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green NHS GMS Expert Review Phenotypes Huntington disease, OMIM:143100 Tags STR
No list HTT_CAG STR in Structural basal ganglia disorders Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.40	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Removed Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR curated_removed
Green HTT_CAG STR in Hereditary spastic paraplegia Level 3: Motor Disorders of the CNS Level 2: Neurology and neurodevelopmental disorders Version 1.316	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green NHS GMS Expert Review Phenotypes Huntington disease, OMIM:143100 Tags STR
No list HTT_CAG STR in Childhood onset hereditary spastic paraplegia Level 2: Neurology Version 8.30 Latest signed off version: v8.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Removed Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR curated_removed
No list HTT_CAG STR in Adult onset hereditary spastic paraplegia Level 2: Neurology Version 6.7 Latest signed off version: v6.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Removed NHS GMS South West GLH London North GLH Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR curated_removed
Green HTT_CAG STR in Adult onset neurodegenerative disorder Level 2: Neurology Version 8.11 Latest signed off version: v8.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Yorkshire and North East GLH NHS GMS London North GLH Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR
No list HTT_CAG STR in Hereditary ataxia with onset in adulthood Level 2: Neurology Version 8.23 Latest signed off version: v8.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Removed London North GLH NHS GMS Wessex and West Midlands GLH Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR curated_removed
No list HTT_CAG STR in Adult onset dystonia, chorea or related movement disorder Level 2: Neurology Version 5.3 Latest signed off version: v5.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Removed NHS GMS London North GLH Expert list Phenotypes Huntington disease, OMIM:143100 Tags STR curated_removed

HTT

23 panels

Red HTT in Parkinson Disease and Complex Parkinsonism

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Phenotypes

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Red HTT in Brain channelopathy

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Phenotypes

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Red HTT in Structural basal ganglia disorders

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Phenotypes

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Red HTT in Paroxysmal central nervous system disorders

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Phenotypes

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Red HTT in Adult onset neurodegenerative disorder

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Phenotypes

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Red HTT in Possible mitochondrial disorder - nuclear genes

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Phenotypes

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Amber HTT in Intellectual disability

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Phenotypes

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Red HTT in Mitochondrial disorders

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Phenotypes

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Red HTT in Hereditary ataxia with onset in adulthood

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Phenotypes

Tags

Red HTT in Adult onset dystonia, chorea or related movement disorder

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Phenotypes

Tags

Amber HTT in Childhood onset dystonia, chorea or related movement disorder

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Phenotypes

Tags

Green HTT_CAG STR in Parkinson Disease and Complex Parkinsonism

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Phenotypes

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Green HTT_CAG STR in Early onset dementia (encompassing fronto-temporal dementia and prion disease)

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Phenotypes

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No list HTT_CAG STR in Brain channelopathy

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Phenotypes

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No list HTT_CAG STR in Ataxia and cerebellar anomalies - narrow panel

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Phenotypes

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Green HTT_CAG STR in Hereditary ataxia

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Phenotypes

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No list HTT_CAG STR in Structural basal ganglia disorders

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Phenotypes

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Green HTT_CAG STR in Hereditary spastic paraplegia

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Phenotypes

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No list HTT_CAG STR in Childhood onset hereditary spastic paraplegia

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Phenotypes

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No list HTT_CAG STR in Adult onset hereditary spastic paraplegia

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