IL1RN

interleukin 1 receptor antagonist
OMIM: 147679, Gene2Phenotype

8 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 8 panels
Green IL1RN in Periodic fever syndromes Level 3: Multi-system inflammatory/autoimmune disorders Level 2: Rheumatological disorders Version 1.34	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other Phenotypes Interleukin 1 receptor antagonist deficiency, OMIM:612852
Green IL1RN in COVID-19 research Level 2: Viral research Version 1.147	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Phenotypes Interleukin 1 receptor antagonist deficiency, OMIM:612852 Sterile multifocal osteomyelitis, periostitis, and pustulosis DIRA Autoinflammatory Disorders
No list IL1RN in Diabetes with additional phenotypes suggestive of a monogenic aetiology Level 3: Disorders of unusual phenotypes Level 2: Endocrine disorders Version 1.68	review	Not set	Sources Expert Review Removed Radboud University Medical Center, Nijmegen Phenotypes {Microvascular complications of diabetes 4}, OMIM:612628 Tags curated_removed
Green IL1RN in Rare genetic inflammatory skin disorders Level 2: Dermatology Version 4.18 Latest signed off version: v4.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources London North GLH NHS GMS Expert Review Green Phenotypes Interleukin 1 receptor antagonist deficiency, OMIM:612852
Green IL1RN in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.88 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Other NHS GMS North West GLH London North GLH IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 Phenotypes Interleukin 1 receptor antagonist deficiency, OMIM:612852 Sterile multifocal osteomyelitis, periostitis, and pustulosis DIRA Autoinflammatory Disorders
Green IL1RN in Skeletal dysplasia Level 2: Musculoskeletal Version 8.38 Latest signed off version: v8.0 (30 Apr 2025) Component of the following Super Panels: Paediatric disorders	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Illumina TruGenome Clinical Sequencing Services Expert list UKGTN Phenotypes Interleukin 1 receptor antagonist deficiency, OMIM:612852
Red IL1RN in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.181 Latest signed off version: v6.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red NHS GMS Phenotypes Interleukin 1 receptor antagonist deficiency, OMIM:612852
Green IL1RN in Autoinflammatory disorders Level 2: Immunology Version 2.35 Latest signed off version: v2.0 (1 May 2024)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Phenotypes Interleukin 1 receptor antagonist deficiency, OMIM:612852