INF2

inverted formin, FH2 and WH2 domain containing
OMIM: 610982, Gene2Phenotype

6 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 6 panels
Red INF2 in Atypical haemolytic uraemic syndrome Level 2: Renal Version 3.9 Latest signed off version: v3.8 (6 May 2026) Component of the following Super Panels: Unexplained young onset end-stage renal disease	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Phenotypes Charcot-Marie-Tooth disease, dominant intermediate E, 614455 Glomerulosclerosis, focal segmental, 5, 613237
Green INF2 in Unexplained kidney failure in young people Level 3: Disorders of function Level 2: Renal and urinary tract disorders Version 1.125	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Emory Genetics Laboratory Illumina TruGenome Clinical Sequencing Services UKGTN Radboud University Medical Center, Nijmegen Eligibility statement prior genetic testing Phenotypes Charcot-Marie-Tooth disease, dominant intermediate E 614455 Glomerulosclerosis, focal segmental, 5 613237
Green INF2 in Hereditary neuropathy Level 3: Motor and Sensory Disorders of the PNS Level 2: Neurology and neurodevelopmental disorders Version 1.508	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS London North GLH Expert Review Green Radboud University Medical Center, Nijmegen Expert list Phenotypes Charcot Marie Tooth disease, dominant intermediate E, 614455
Red INF2 in Intellectual disability Level 2: Developmental disorders Version 10.2 Latest signed off version: v10.0 (6 May 2026) Component of the following Super Panels: Childhood onset leukodystrophy Hypotonic infant Paediatric disorders	review	Not set	Sources Expert Review Red Radboud University Medical Center, Nijmegen Phenotypes Glomerulosclerosis, focal segmental, 5, 613237Charcot-Marie-Tooth disease, dominant intermediate E, 614455
Green INF2 in Proteinuric renal disease Level 2: Renal Version 6.1 Latest signed off version: v6.0 (6 May 2026) Component of the following Super Panels: Unexplained young onset end-stage renal disease	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Green Eligibility statement prior genetic testing Phenotypes Glomerulosclerosis, focal segmental, 5 #613237 Adult onset nephrotic syndrome (+CMT) FSGS proteinuria renal failure
Green INF2 in Hereditary neuropathy or pain disorder Level 2: Neurology Version 8.1 Latest signed off version: v8.0 (6 May 2026)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Radboud University Medical Center, Nijmegen Expert Review Green Expert list London North GLH NHS GMS NHS GMS London North GLH Phenotypes Charcot Marie Tooth disease, dominant intermediate E, 614455