IRF4

interferon regulatory factor 4
OMIM: 601900, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Green IRF4 in COVID-19 research


Level 2: Viral research
Version 1.142

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • IUIS Classification December 2019
  • Expert Review Green
Phenotypes
  • Defects in intrinsic and innate immunity
  • IRF4 haploinsufficiency
  • inborn errors of immunity related to leukocytes
Red IRF4 in Pigmentary skin disorders


Version 3.12
Latest signed off version: v3.0 (22 Mar 2023)

review Not set
Sources
  • London North GLH
  • Expert Review Red
  • NHS GMS
Phenotypes
  • Pigmentation,susceptibility to facial pigmented spots
Green IRF4 in Primary immunodeficiency or monogenic inflammatory bowel disease


Version 5.3
Latest signed off version: v5.0 (1 May 2024)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • NHS GMS
  • Expert list
Phenotypes
  • combined immunodeficiency, MONDO:0015131
No list IRF4 in Multiple monogenic benign skin tumours


Version 2.4
Latest signed off version: v2.0 (30 Nov 2022)

review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Removed
  • London North GLH
  • NHS GMS
Phenotypes
  • Pigmentation, susceptibility to facial pigmented spots
Tags
  • curated_removed