1. Genes and Genomic Entities
  2. KCNE3

KCNE3

potassium voltage-gated channel subfamily E regulatory subunit 3
OMIM: 604433, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Red KCNE3 in Familial Meniere Disease

Level 3: Other hearing and ear disorders
Level 2: Hearing and ear disorders
Version 1.3

review Not set
Sources
  • Literature
Red KCNE3 in Short QT syndrome


Version 3.10
Latest signed off version: v3.1 (22 Mar 2023)

Component of the following Super Panels:

  • Cardiac arrhythmias
  • Sudden unexplained death or survivors of a cardiac event

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • North West GLH
    • Brugada syndrome (Version 1.7)
    • Long QT syndrome (Version 1.5)
    Phenotypes
    • ?Brugada syndrome 6 (613119)
    Red KCNE3 in Long QT syndrome

    Level 3: Cardiac arrhythmia
    Level 2: Cardiovascular disorders
    Version 3.7
    Latest signed off version: v3.1 (22 Mar 2023)

    Component of the following Super Panels:

  • Cardiac arrhythmias
  • Sudden unexplained death or survivors of a cardiac event
  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review Unknown
    Sources
    • South West GLH
    • Literature
    Phenotypes
    • Long QT syndrome
    • Brugada syndrome
    Red KCNE3 in Brugada syndrome and cardiac sodium channel disease

    Level 3: Cardiac arrhythmia
    Level 2: Cardiovascular disorders
    Version 3.8
    Latest signed off version: v3.2 (22 Mar 2023)

    Component of the following Super Panels:

  • Cardiac arrhythmias
  • Sudden unexplained death or survivors of a cardiac event

    		•  review Unknown
    Sources
    • Expert Review Red
    • South West GLH
    • London South GLH
    • North West GLH
    • Expert list
    • Emory Genetics Laboratory
    • Radboud University Medical Center, Nijmegen
    • UKGTN
    • Illumina TruGenome Clinical Sequencing Services
    Phenotypes
    • ?Brugada syndrome 6, OMIM:613119