1. Genes and Genomic Entities
  2. LRIG2

LRIG2

leucine rich repeats and immunoglobulin like domains 2
OMIM: 608869, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels
Green LRIG2 in Unexplained kidney failure in young people

Level 3: Disorders of function
Level 2: Renal and urinary tract disorders
Version 1.124

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Radboud University Medical Center, Nijmegen
  • Expert Review
Phenotypes
  • Urofacial syndrome 2 615112
Green LRIG2 in CAKUT

Level 3: Structural renal and urinary tract disease
Level 2: Renal and urinary tract disorders
Version 1.181

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Expert Review
Phenotypes
  • Urofacial syndrome
  • Congenital bladder disease: dyssynergic, high pressure bladder.
Amber LRIG2 in Fetal anomalies


Level 2: Fetal (including NIPD)
Version 6.163
Latest signed off version: v6.0 (30 Apr 2025)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • Expert Review Amber
  • PAGE DD-Gene2Phenotype
Phenotypes
  • Urofacial syndrome 2, OMIM:615112
Green LRIG2 in DDG2P


Version 6.432
Latest signed off version: v6.0 (30 Apr 2025)

Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • DD-Gene2Phenotype
    Phenotypes
    • UROFACIAL SYNDROME 236730
    Green LRIG2 in Paediatric disorders - additional genes


    Level 2: Developmental disorders
    Version 7.35
    Latest signed off version: v7.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Other
    Phenotypes
    • CAKUT
    • Urofacial syndrome 2, 615112
    • Congenital bladder disease: dyssynergic, high pressure bladder.
    • Urofacial syndrome
    Green LRIG2 in Unexplained young onset end-stage renal disease - additional genes


    Level 2: Renal
    Version 1.6
    Latest signed off version: v1.1 (30 Apr 2025)

    Component of the following Super Panels:

  • Unexplained young onset end-stage renal disease

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    Phenotypes
    • Urofacial syndrome 2, OMIM:615112
    • Congenital bladder disease: dyssynergic, high pressure bladder