LRIG2

leucine rich repeats and immunoglobulin like domains 2
OMIM: 608869, Gene2Phenotype

8 panels

Panel Reviews Mode of inheritance Details
8 panels
Green LRIG2 in Unexplained kidney failure in young people

Level 3: Disorders of function
Level 2: Renal and urinary tract disorders
Version 1.117

Component of the following Super Panels:

  • Renal superpanel - broad
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Radboud University Medical Center, Nijmegen
    • Expert Review
    Phenotypes
    • Urofacial syndrome 2 615112
    Green LRIG2 in CAKUT

    Level 3: Structural renal and urinary tract disease
    Level 2: Renal and urinary tract disorders
    Version 1.173

    Component of the following Super Panels:

  • Renal superpanel - broad
  • Renal superpanel - narrow
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert Review
    Phenotypes
    • Urofacial syndrome
    • Congenital bladder disease: dyssynergic, high pressure bladder.
    Green LRIG2 in Unexplained young onset end-stage renal disease


    Version 3.37
    Latest signed off version: v3.0 (22 Mar 2023)

    Component of the following Super Panels:

  • Renal superpanel - broad
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert Review Green
    Phenotypes
    • Urofacial syndrome
    • Urofacial syndrome 2 615112
    • Congenital bladder disease: dyssynergic, high pressure bladder.
    Amber LRIG2 in Fetal anomalies


    Version 3.135
    Latest signed off version: v3.0 (22 Mar 2023)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Amber
    • PAGE DD-Gene2Phenotype
    Phenotypes
    • Urofacial syndrome 2, OMIM:615112
    Green LRIG2 in DDG2P


    Version 3.79
    Latest signed off version: v3.1 (22 Mar 2023)

    Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • DD-Gene2Phenotype
    Phenotypes
    • UROFACIAL SYNDROME 236730
    Green LRIG2 in Paediatric disorders - additional genes


    Version 3.9
    Latest signed off version: v3.0 (22 Mar 2023)

    Component of the following Super Panels:

  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Other
    Phenotypes
    • CAKUT
    • Urofacial syndrome 2, 615112
    • Congenital bladder disease: dyssynergic, high pressure bladder.
    • Urofacial syndrome
    Red LRIG2 in Groopman et al 2019 - Genes with diagnostic variants


    Version 0.8

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • Expert review red
    • Literature
    Phenotypes
    • Congenital or cystic renal disease
    • MIM 615112
    • Urofacial syndrome 2
    Green LRIG2 in Severe Paediatric Disorders


    Version 1.182

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Next Generation Children Project
    • Expert Review Green
    • Expert list
    Phenotypes
    • Urofacial syndrome 2, 615112