1. Genes and Genomic Entities
  2. MYD88

MYD88

myeloid differentiation primary response 88
OMIM: 602170, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels
Red MYD88 in Familial Meniere Disease

Level 3: Other hearing and ear disorders
Level 2: Hearing and ear disorders
Version 1.3

review Not set
Sources
  • Literature
Green MYD88 in COVID-19 research


Level 2: Viral research
Version 1.142

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • IUIS Classification February 2018
  • A- or hypo-gammaglobulinaemia v1.25
  • London North GLH
  • NHS GMS
  • GRID V2.0
  • Victorian Clinical Genetics Services
  • North West GLH
  • ESID Registry 20171117
  • Expert Review Green
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
  • A- or hypo-gammaglobulinaemia v1.25
Phenotypes
  • recurrent pyogenic bacterial infection
  • Defects of TLR/NFkappa-B signalling
  • Defects in Intrinsic and Innate Immunity
  • Bacterial infections (pyogens)
  • Pyogenic bacterial infections, recurrent, due to MYD88 deficiency 612260
Green MYD88 in Primary immunodeficiency or monogenic inflammatory bowel disease


Version 4.202
Latest signed off version: v4.0 (22 Mar 2023)

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • NHS GMS
  • North West GLH
  • London North GLH
  • IUIS Classification February 2018
  • Victorian Clinical Genetics Services
  • Expert Review Green
  • ESID Registry 20171117
  • GRID V2.0
  • A- or hypo-gammaglobulinaemia v1.25
Phenotypes
  • Pyogenic bacterial infections, recurrent, due to MYD88 deficiency 612260
  • Defects of TLR/NFkappa-B signalling
  • recurrent pyogenic bacterial infection
  • Bacterial infections (pyogens)
  • Defects in Intrinsic and Innate Immunity
Red MYD88 in Cytopenias and congenital anaemias

Level 3: Anaemias and red cell disorders
Level 2: Haematological disorders
Version 1.118

review Not set
Sources
  • Expert Review Red
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Pyogenic bacterial infections, recurrent, due to MYD88 deficiency, 612260
  • Macroglobulinemia, Waldenstrom, somatic, 153600
Green MYD88 in Severe Paediatric Disorders


Version 1.184

review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Pyogenic bacterial infections, recurrent, due to MYD88 deficiency, 612260