NCF4

neutrophil cytosolic factor 4
OMIM: 601488, Gene2Phenotype

4 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 4 panels
Red NCF4 in Infantile enterocolitis & monogenic inflammatory bowel disease Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.45	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Red UKGTN Radboud University Medical Center, Nijmegen Illumina TruGenome Clinical Sequencing Services Emory Genetics Laboratory Expert list Phenotypes Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type III 613960
Amber NCF4 in Gastrointestinal epithelial barrier disorders Level 3: Gastrointestinal disorders Level 2: Gastroenterological disorders Version 1.76	review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Amber UKGTN Emory Genetics Laboratory Phenotypes Early Onset Inflammatory Bowel Disease Inflammatory Bowel Disease (Very Early Onset) Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type III 613960
Green NCF4 in COVID-19 research Level 2: Viral research Version 1.147	review	BIALLELIC, autosomal or pseudoautosomal	Sources IUIS Classification February 2018 London North GLH GOSH PID v.8.0 NHS GMS GRID V2.0 Victorian Clinical Genetics Services North West GLH ESID Registry 20171117 Expert Review Green NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes Infections, autoinflammatory phenotype Congenital defects of phagocyte number or function ?Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type III 613960 Chronic granulomatous disease (CGD) Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type III
Green NCF4 in Primary immunodeficiency or monogenic inflammatory bowel disease Level 2: Immunology Version 8.88 Latest signed off version: v8.0 (30 Apr 2025)	review	BIALLELIC, autosomal or pseudoautosomal	Sources NHS GMS North West GLH London North GLH Expert Review Green IUIS Classification February 2018 Victorian Clinical Genetics Services ESID Registry 20171117 GRID V2.0 GOSH PID v.8.0 Phenotypes ?Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type III 613960 Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type III Chronic granulomatous disease (CGD) Infections, autoinflammatory phenotype Congenital defects of phagocyte number or function