Infantile enterocolitis & monogenic inflammatory bowel disease
Gene: NCF4Comment on list classification: Only one case report at this time. Several positive and negative gene association studies in inflammatory bowel disease, crohn's disease, colitis patients.Created: 13 Oct 2016, 3:42 p.m.
Associated with phenotype in OMIM, not in G2P / DD. Present on UKGTN Very Early Onset Inflammatory Bowel Disease 40 Gene Panel and Emory Genetics Laboratory Early Onset Inflammatory Bowel Disease: Sequencing Panel. Two variants reported in one compound heterozygous case.Created: 5 Sep 2016, 8:33 a.m.
14th Oct 2016: panel revised according to expert review, additional curation for evidence level and internal clinical review, and promoted to version 1.
This gene has been classified as Red List (Low Evidence).
This gene has been classified as Amber List (Moderate Evidence).
Publications for NCF4 were set to 19692703 (case report);18580884;19262523;21900546;26289093; 21472827;21122541;19262523;17435756
Publications for NCF4 were set to 19692703 (case report);18580884;19262523;21900546;26289093; 21472827;21122541;19262523;17435756
This gene has been classified as Amber List (Moderate Evidence).
NCF4 was added to Infantile enterocolitis & monogenic inflammatory bowel diseasepanel. Sources: Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,UKGTN
Phenotypes for gene NCF4 were set to Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type III 613960
NCF4 was created by ellenmcdonagh
NCF4 was added to Infantile enterocolitis & monogenic inflammatory bowel diseasepanel. Sources: Expert list