Infantile enterocolitis & monogenic inflammatory bowel disease
Gene: IL10RB
Associated with phenotype in OMIM, not in G2P / DD. Present on UKGTN Very Early Onset Inflammatory Bowel Disease 40 Gene Panel. Numerous four homozygous variants reportedCreated: 5 Sep 2016, 6:56 a.m.
Comment on phenotypes: Also associated with Hepatitis B virus, susceptibility to 610424Created: 2 Sep 2016, 11:45 a.m.
14th Oct 2016: panel revised according to expert review, additional curation for evidence level and internal clinical review, and promoted to version 1.
Phenotypes for IL10RB were set to IL-10 signalling defects / deficiency; Inflammatory bowel disease 25, early onset, autosomal recessive 612567
This gene has been classified as Green List (High Evidence).
Phenotypes for gene IL10RB were set to IL-10 signalling defects / deficiency; Inflammatory bowel disease 25, early onset, autosomal recessive 612567
IL10RB was added to Infantile enterocolitis & monogenic inflammatory bowel diseasepanel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,UKGTN
This gene has been classified as Red List (Low Evidence).
This gene has been classified as Green List (High Evidence).
Phenotypes for gene IL10RB were set to IL-10 signalling defects
IL10RB was added to Infantile enterocolitis & monogenic inflammatory bowel diseasepanel. Sources: Eligibility statement prior genetic testing
IL10RB was created by ellenmcdonagh
IL10RB was added to Infantile enterocolitis & monogenic inflammatory bowel diseasepanel. Sources: Expert list