PROS1

protein S
OMIM: 176880, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Green PROS1 in Inherited bleeding disorders

Level 3: Haemostasis disorders
Level 2: Haematological and immunological disorders
Version 1.159

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Eligibility statement prior genetic testing
  • UKGTN
  • Radboud University Medical Center, Nijmegen
  • Illumina TruGenome Clinical Sequencing Services
  • Expert Review Green
  • BRIDGE Study Tier 1 Gene
Phenotypes
  • Protein S deficiency
  • Thrombophilia Due To Protein S Deficiency, Autosomal Dominant
  • Thrombophilia Due To Protein S Deficiency, Autosomal Recessive
  • Thrombophilia due to protein S deficiency, autosomal dominant 612336
  • Thrombophilia due to protein S deficiency, autosomal recessive 614514
  • Protein S Deficiency

Green PROS1 in Thrombophilia


Version 1.19
Latest signed off version: v1.2 (3 Mar 2020)

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • North West GLH
  • Yorkshire and North East GLH
  • London South GLH
  • NHS GMS
  • Expert Review Green
  • Wessex and West Midlands GLH
Phenotypes
  • Thrombophilia due to protein S deficiency, autosomal dominant, OMIM:612336
  • Thrombophilia due to protein S deficiency, autosomal recessive, OMIM:614514

Green PROS1 in Severe Paediatric Disorders


Version 1.76

review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Next Generation Children Project
  • Expert Review Green
  • Expert list
Phenotypes
  • Thrombophilia due to protein S deficiency, autosomal dominant, 612336
  • Thrombophilia due to protein S deficiency, autosomal recessive, 614514