RNU7-1

RNA, U7 small nuclear 1
Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels
Green RNU7-1 in White matter disorders and cerebral calcification - childhood onset


Level 2: Neurology
Version 8.7
Latest signed off version: v8.6 (12 Aug 2026)

Component of the following Super Panels:

  • Leukodystrophy, childhood onset
  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Aicardi-Goutieres syndrome 9, OMIM:619487
    • Type I interferonopathy
    Tags
    • locus-type-rna-small-nuclear
    Green RNU7-1 in Primary immunodeficiency or monogenic inflammatory bowel disease


    Level 2: Immunology
    Version 9.102
    Latest signed off version: v9.91 (12 Aug 2026)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Aicardi-Goutieres syndrome 9, OMIM:619487
    • Type I interferonopathy
    Tags
    • locus-type-rna-small-nuclear
    Green RNU7-1 in Hereditary spastic paraplegia, childhood onset


    Level 2: Neurology
    Version 9.11
    Latest signed off version: v9.7 (12 Aug 2026)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Aicardi-Goutieres syndrome 9, OMIM:619487
    • Type I interferonopathy
    Tags
    • locus-type-rna-small-nuclear
    Green RNU7-1 in Fetal anomalies


    Level 2: Fetal (including NIPD)
    Version 8.5
    Latest signed off version: v8.0 (12 Aug 2026)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    Phenotypes
    • Aicardi-Goutieres syndrome 9, OMIM:619487
    • Type I interferonopathy
    Tags
    • locus-type-rna-small-nuclear
    Green RNU7-1 in Intellectual disability


    Level 2: Developmental disorders
    Version 11.26
    Latest signed off version: v11.0 (12 Aug 2026)

    Component of the following Super Panels:

  • Hypotonic infant
  • Leukodystrophy, childhood onset
  • Paediatric disorders
  • review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Aicardi-Goutieres syndrome 9, OMIM:619487
    • Type I interferonopathy
    Tags
    • locus-type-rna-small-nuclear
    Green RNU7-1 in Dystonia, chorea or related movement disorder, childhood onset


    Level 2: Neurology
    Version 8.14
    Latest signed off version: v8.13 (12 Aug 2026)

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Aicardi-Goutieres syndrome 9, OMIM:619487
    • Type I interferonopathy
    Tags
    • locus-type-rna-small-nuclear