1. Genes and Genomic Entities
  2. RRAGC

RRAGC

Ras related GTP binding C
OMIM: 608267, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels
Amber RRAGC in Dilated and arrhythmogenic cardiomyopathy


Level 2: Cardiology
Version 3.11
Latest signed off version: v3.0 (30 Apr 2025)

Component of the following Super Panels:

  • Sudden unexplained death or survivors of a cardiac event
  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Amber
    • Literature
    • NHS GMS
    Phenotypes
    • Dilated cardiomyopathy, hepatopathy and brain abnormalities
    Green RRAGC in Fetal anomalies


    Level 2: Fetal (including NIPD)
    Version 6.140
    Latest signed off version: v6.0 (30 Apr 2025)

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • NHS GMS
    Phenotypes
    • Long-Olsen syndrome, OMIM:620609
    Green RRAGC in DDG2P


    Version 6.424
    Latest signed off version: v6.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Paediatric disorders

    		•  review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • DD-Gene2Phenotype
    • Expert Review Green
    Phenotypes
    • RRAGC-related congenital dilated cardiomyopathy with hyperlactatemia, deranged liver function and cataracts
    Tags
    • de novo
    Green RRAGC in Paediatric or syndromic cardiomyopathy


    Level 2: Cardiology
    Version 7.96
    Latest signed off version: v7.0 (30 Apr 2025)

    Component of the following Super Panels:

  • Unexplained death in infancy and sudden unexplained death in childhood

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Literature
    • NHS GMS
    Phenotypes
    • Long-Olsen syndrome, OMIM:620609