SCN10A

sodium voltage-gated channel alpha subunit 10
OMIM: 604427, Gene2Phenotype

7 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 7 panels
Red SCN10A in Short QT syndrome Version 3.10 Latest signed off version: v3.1 (22 Mar 2023) Component of the following Super Panels: Cardiac arrhythmias Sudden unexplained death or survivors of a cardiac event	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources North West GLH Expert Review Red Brugada syndrome (Version 1.7) Literature Phenotypes J wave syndrome short QT Episodic pain syndrome, familial, 2 (615551) sudden death
Red SCN10A in Brugada syndrome and cardiac sodium channel disease Level 3: Cardiac arrhythmia Level 2: Cardiovascular disorders Version 3.8 Latest signed off version: v3.2 (22 Mar 2023) Component of the following Super Panels: Cardiac arrhythmias Sudden unexplained death or survivors of a cardiac event	review	Unknown	Sources Expert Review Red South West GLH London South GLH North West GLH Oxford Medical Genetics Laboratory Phenotypes Brugada syndrome, MONDO:0015263
Green SCN10A in Pain syndromes Level 3: Channelopathies Level 2: Neurology and neurodevelopmental disorders Version 1.12	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green BRIDGE Study Tier 1 Gene Phenotypes Familial episodic pain syndrome-2 Episodic pain syndrome, familial, 2, 615551 Painful small fibre neuropathy SFN Small fibre neuropathy
Red SCN10A in Paroxysmal central nervous system disorders Version 3.10 Latest signed off version: v3.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Red NHS GMS London North GLH Wessex and West Midlands GLH Phenotypes Painful small fibre neuropathy SFN Small fibre neuropathy Familial episodic pain syndrome-2 Episodic pain syndrome, familial, 2, 615551
Green SCN10A in Hereditary neuropathy Level 3: Motor and Sensory Disorders of the PNS Level 2: Neurology and neurodevelopmental disorders Version 1.477	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green NHS GMS London North GLH Phenotypes Episodic pain syndrome, familial, 2, 615551
Green SCN10A in Hereditary neuropathy or pain disorder Version 3.94 Latest signed off version: v3.24 (15 May 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green London North GLH NHS GMS NHS GMS London North GLH Phenotypes Episodic pain syndrome, familial, 2, 615551
Red SCN10A in Paediatric pseudo-obstruction syndrome Version 1.5 Latest signed off version: v1.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert list Phenotypes Colon sensory neurons activation